Hot Products

Bruceantinol
Catalog No: CFN89336

Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL. Bruceantinol shows in vitro inhibitory activity against Trypanosoma evansi.

Bruceantinol B
Catalog No: CFN95216

Reference standards.

Bruceantinoside A
Catalog No: CFN89343

Bruceantinoside A has antileukemic activity.

Bruceine A
Catalog No: CFN89338

Bruceine A has antibabesial activity, it can inhibit the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration and kill the parasites within 24 hr at a concentration of 25 nM; it show strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM. Bruceine A has anthelmintic activity, it exhibits significant activity against Dactylogyrus intermedius with EC(50) values of 0.49 mg/L. Bruceine A exhibits NF-κB p65 inhibition, and cytotoxic potential against HT-29, HeLa, and HL-60 cells .

Bruceine B
Catalog No: CFN89335

Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC. Bruceine B exhibits potent anti-malarial activities with high selective toxicities; it also shows strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM. Bruceine B shows strong antiviral activities, with IC(50) values in the range of 3.42-5.66 microM.

Bruceine D
Catalog No: CFN90771

Bruceine D has anti-cancer activity, it inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.Bruceine D may have the potential to be used as a natural viricide, or a lead compound for new viricides.

Bruceine E
Catalog No: CFN89340

Bruceine E exhibits significant blood glucose concentration reduction activity, it might act as an insulin secretagogue.

Bruceine J
Catalog No: CFN91973

Reference standards.

Brucine
Catalog No: CFN90244

Brucine has anti-cncer activity, it can treat hepatocellular carcinoma (HCC) and inhibit the proliferation of human lung cancer cell line PC-9 mainly by blocking the cell cycle at G0/G1 via down-regulating the expression of Cyclin D1, Cyclin E.

Brucine sulfate
Catalog No: CFN90316

Brucine sulfate is a product from Strychnos nux-vomica L.