Cajanin
Catalog No: CFN98419
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug. Cajanin has strong mitogenic as well as differentiation-promoting effects on osteoblasts that involved subsequent activation of MEK-Erk and Akt pathways.
Calceolarioside A
Catalog No: CFN98522
Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly related to a calcium-dependent mechanism. Calceolarioside A also has potent antioxidative activity, it displays stronger scavenging potential with IC50 values of (4.15 +/- 0.07, 40.32 +/- 0.09, 2.26 +/- 0.03 microM) for OH, total ROS and scavenging of ONOO(-), respectively.
Calcium pantothenate
Catalog No: CFN91751
Calcium pantothenate, a vitamin, can reduce the patulin content of the apple juice.In vitro: In human dermal fibroblasts from three different donors, Calcium pantothenate accelerates the wound healing process by increasing the number of migrating cells, their distance and hence their speed. In addition, cell division is increased and the protein synthesis changed.Pantothenic acid shows anti-radiation and antioxidant effects, which can protect cells from cell damage induced by reactive oxygen species
IC50 & Target: Human Endogenous Metabolite
Calenduloside E
Catalog No: CFN91169
Calenduloside E, a potent anti-apoptotic agent, has anti-tumour and anti-angiogenic activities, it can protect against ox-LDL-induced human umbilical vein endothelial cell (HUVEC) injury in our previous reports. Calenduloside E has anti-inflammary activity, it inhibits LPS-induced inflammatory response by blocking ROS-mediated activation of JAK1-stat3 signaling pathway in RAW264.7 cells. Calenduloside E analogues provide protection to H9c2 cardiomyocytes against H2O2-induced oxidative stress and apoptosis, most likely via anti-apoptotic mechanism.