beta-Estradiol
Catalog No: CFN90035
Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. Beta-estradiol has been considered to be a neurotrophic agent, beta-estradiol at a dose of 0.25 microg/day prevents ischemia-induced learning disability and neuronal loss at early stages after transient forebrain ischemia, possibly via a receptor-mediated pathway without attenuating free radical neurotoxicity.
Beta-Hydroxyisovalerylshikonin
Catalog No: CFN93028
Beta-Hydroxyisovalerylshikonin is an ATP non-competitive inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines.
Beta-Hydroxyisovalerylshikonin has anti-adipogenic, antiinflammatory and antitumor effects, it activated AMPK, which was followed by the downregulation of mature SREBP‑1c and fat-forming enzymes, leading to the inhibition of adipogenesis. Beta-Hydroxyisovalerylshikonin can significantly decrease viability of HCT116 cells (IC50 values of 30.9 ug/mL).