Calcium pantothenate
Catalog No: CFN91751
Calcium pantothenate, a vitamin, can reduce the patulin content of the apple juice.In vitro: In human dermal fibroblasts from three different donors, Calcium pantothenate accelerates the wound healing process by increasing the number of migrating cells, their distance and hence their speed. In addition, cell division is increased and the protein synthesis changed.Pantothenic acid shows anti-radiation and antioxidant effects, which can protect cells from cell damage induced by reactive oxygen species
IC50 & Target: Human Endogenous Metabolite
Calenduloside E
Catalog No: CFN91169
Calenduloside E, a potent anti-apoptotic agent, has anti-tumour and anti-angiogenic activities, it can protect against ox-LDL-induced human umbilical vein endothelial cell (HUVEC) injury in our previous reports. Calenduloside E has anti-inflammary activity, it inhibits LPS-induced inflammatory response by blocking ROS-mediated activation of JAK1-stat3 signaling pathway in RAW264.7 cells. Calenduloside E analogues provide protection to H9c2 cardiomyocytes against H2O2-induced oxidative stress and apoptosis, most likely via anti-apoptotic mechanism.
Calycosin
Catalog No: CFN99140
Calycosin, a selective estrogen receptor modulator, is also a vasorelaxant and a noncompetitive Ca(2+) channel blocker. It has anti-oxidative, anti-inflammatory, hepatoprotective,antineoplastic, and effective skin-lightening activities. Calycosin exhibited tyrosinase inhibitory activity with an IC(50) value of 38.4 microM, it suppressed breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways.
Calystegine B1
Catalog No: CFN00164
Calystegine B1 is a noncompetitive inhibitor of rice alpha-glucosidase, with a Ki value of 0.9 +/- 0.1 microM. Calystegine B1 and Calystegine C1 are potent competitive inhibitors of the bovine, human, and rat beta-glucosidase activities, with Ki values of 150, 10, and 1.9 microM.