Bisabolangelone
Catalog No: CFN91876
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling. Bisabolangelone has antimelanogenic activity, the cAMP-binding site of PKA as a putative target ameliorating melanocyte-specific hyperpigmented disorder. Bisabolangelone has anti-ulcer activity, it is possible that bisabolangelone inhibited the activity of the H(+)/K(+)-ATPase, then reducing the secretion of H(+). It also inhibits the activity of 5alpha-reductase type I in LNCaP cells (IC50 = 11.6 microg/ml).
Bisdemethoxycurcumin
Catalog No: CFN99186
Bisdemethoxycurcumin is a natural derivative of curcumin with antiulcer, antioxidant, anti-inflammatory and anti-cancer activities, it suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Bisdemethoxycurcumin induces apoptosis in activated HSCs, but not in hepatocytes, by impairing cellular energetics and causing a downregulation of cytoprotective proteins, likely through a mechanism that involves CBR2.
Bixin
Catalog No: CFN91597
Bixin (BX), isolated from the seeds of Bixa orellana, is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation. Bixin functions as a potent antagonist of PI3K/Akt signaling to protect against allergic asthma.
