Hot Products

Calycosin
Catalog No: CFN99140

Calycosin, a selective estrogen receptor modulator, is also a vasorelaxant and a noncompetitive Ca(2+) channel blocker. It has anti-oxidative, anti-inflammatory, hepatoprotective,antineoplastic, and effective skin-lightening activities. Calycosin exhibited tyrosinase inhibitory activity with an IC(50) value of 38.4 microM, it suppressed breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways.

Calycosin-7-O-beta-D-glucoside
Catalog No: CFN99141

Calycosin-7-O-beta-D-glucoside, a melanin biosynthesis inhibitor, can protect BBB integrity in experimental cerebral ischemia–reperfusion injury via regulating NO/cav-1/MMPs pathway. It attenuates ischemia-reperfusion injuryin vivovia activation of the PI3K/Akt pathway, and has effects on cell apoptosis in cervical cancer HeLa cells and expression of Bcl-2/Bax.

Calystegine A3
Catalog No: CFN00166

Calystegines A3, B2, and C1 are glycosidase inhibitors. Calystegines A3 and B2 can effectively stabilize β-glucocerebrosidase, and consequently increase intracellular β-glucocerebrosidase activities in N370S fibroblasts.

Calystegine A5
Catalog No: CFN00169

Reference standards.

Calystegine B1
Catalog No: CFN00164

Calystegine B1 is a noncompetitive inhibitor of rice alpha-glucosidase, with a Ki value of 0.9 +/- 0.1 microM. Calystegine B1 and Calystegine C1 are potent competitive inhibitors of the bovine, human, and rat beta-glucosidase activities, with Ki values of 150, 10, and 1.9 microM.

Calystegine B2
Catalog No: CFN00161

Calystegine B2 can inhibit the alpha-galactosidase and enzymes beta-glucosidase activities.

Calystegine B3
Catalog No: CFN00162

Calystegine B3 is a highly specific inhibitor for Man2C1 among various α-mannosidases prepared from rat liver, it could thus serve as a potent tool for the development of a highly specific in vivo inhibitor for Man2C1.

Calystegine B4
Catalog No: CFN00163

Calystegine B4 inhibits almond beta-glucosidase and pig kidney trehalase in a competitive manner, with a Ki value of 7.3 microM and 1.2 microM, respectively.

Calyxin B
Catalog No: CFN99693

Calyxin B exhibits potent activity against human HT-1080 fibrosarcoma cells with an ED50 value of 0.69 microM. A methylated product of calyxin A and an epimeric mixture of Calyxin B, showed greatly reduced activity suggesting that phenolic hydroxyl groups are involved in the inhibitory activity.

Camaldulenic acid
Catalog No: CFN96017

Standard reference