Hot Products

Blumenol B
Catalog No: CFN98491

Standard reference

Blumenol C glucoside
Catalog No: CFN99424

Reference standards.

Bocconoline
Catalog No: CFN95373

Bocconoline strongly perturbs various cellular components of human olfactory neurosphere-derived (hONS) cell lines. Bocconoline exhibited good inhibitory activity in the leukaemia cell line HEL.Bocconoline has anticancer activity .

Boehmenan
Catalog No: CFN98963

(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.

Boeravinone B
Catalog No: CFN96206

Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development. Boeravinone B exhibits significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model.

Boldine
Catalog No: CFN98718

Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities. Boldine reduces oxidative stress and improves endothelium-dependent relaxation in aortas of diabetic mice largely through inhibiting ROS overproduction associated with Ang II-mediated BMP4-dependent mechanisms. Boldine may attenuate the catecholamine oxidation-induced brain mitochondrial dysfunction and decrease the dopamine-induced death of PC12 cells through a scavenging action on reactive oxygen species and inhibition of melanin formation and thiol oxidation.

Borapetoside B
Catalog No: CFN96298

Standard reference

Borneol
Catalog No: CFN98116

(+)-Borneol is a bicyclic monoterpene used for analgesia and anaesthesia in traditional Chinese and Japanese medicine, it and its enantiomer (-)-borneol have a highly efficacious positive modulating action at GABA(A) receptors at human recombinant alpha1beta2gamma2L GABA(A) receptors. Borneol specifically inhibits the nicotinic acetylcholine receptor (nAChR)-mediated effects in a noncompetitive way, can depress P-glycoprotein function by a NF-κB signaling mediated mechanism in a blood brain barrier in vitro model. Borneol has neuroprotection through the inhibition of IκBα-NF-κB and translocation signaling pathway, it also has an anti-cerebral ischemia effects. It can suppresse inflammatory responses in LPS-induced acute lung injury through inhibition of the NF-κB and MAPKs signaling pathways.

Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside
Catalog No: CFN90909

Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis.

Bornyl acetate
Catalog No: CFN90494

Bornyl acetate shows highly active whitening and antioxidant activities, has potential applications in cosmeceutical materials. Bornyl acetate has anti-inflammatory activity, may be developed as a preventive agent for lung inflammatory diseases and osteoarthritis; it also has an antiabortive effect through modulation of immunological balance at maternal-fetal interface.