Salvianolic acid Y

Salvianolic acid Y
Product Name Salvianolic acid Y
CAS No.: 1638738-76-7
Catalog No.: CFN91004
Molecular Formula: C36H30O16
Molecular Weight: 718.6 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The roots of Salvia miltiorrhiza Bge.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $333/5mg
Salvianolic acid Y is a new protector of PC12 cells against hydrogen peroxide-induced injury from Salvia officinalis.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Sci Rep.2019, 9(1):4646
  • Molecules.2017, 22(3)
  • Food Chem.2019, 275:746-753
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Planta Med.2018, 84(15):1101-1109
  • Life Sci.2019, 216:259-270
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Chemistry of Natural Compounds2018, 204ĘC206
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Methyl salvionolate A

    Catalog No: CFN92564
    CAS No: 1015171-69-3
    Price: Inquiry(manager@chemfaces.com)
    Isosalvianolic acid C

    Catalog No: CFN92565
    CAS No: 142115-17-1
    Price: Inquiry(manager@chemfaces.com)
    Salvianolic acid C

    Catalog No: CFN98553
    CAS No: 115841-09-3
    Price: $208/20mg
    Lithospermic acid

    Catalog No: CFN98546
    CAS No: 28831-65-4
    Price: $138/20mg
    Monomethyl lithospermate

    Catalog No: CFN91005
    CAS No: 933054-33-2
    Price: $333/10mg
    Salvianolic acid Y

    Catalog No: CFN91004
    CAS No: 1638738-76-7
    Price: $333/5mg
    Salvianolic acid B

    Catalog No: CFN99332
    CAS No: 115939-25-8
    Price: $80/20mg
    Magnesium Lithospermate B

    Catalog No: CFN90390
    CAS No: 122021-74-3
    Price: Inquiry(manager@chemfaces.com)
    9'-Methyl lithospermate B

    Catalog No: CFN90691
    CAS No: 1167424-31-8
    Price: $168/10mg
    9'''-Methyl salvianolate B

    Catalog No: CFN90810
    CAS No: 1167424-32-9
    Price: $218/10mg
    Molecules. 2015 Jan 6;20(1):683-92.
    Salvianolic acid Y: a new protector of PC12 cells against hydrogen peroxide-induced injury from Salvia officinalis.[Pubmed: 25569522 ]
    Salvianolic acid Y (TSL 1), a new phenolic acid with the same planar structure as salvianolic acid B, was isolated from Salvia officinalis.
    METHODS AND RESULTS:
    The structural elucidation and stereochemistry determination were achieved by spectroscopic and chemical methods, including 1D, 2D-NMR (1H-1H COSY, HMQC and HMBC) and circular dichroism (CD) experiments. The biosynthesis pathway of salvianolic acid B and Salvianolic acid Y (TSL 1) was proposed based on structural analysis. The protection of PC12 cells from injury induced by H2O2 was assessed in vitro using a cell viability assay.
    CONCLUSIONS:
    Salvianolic acid Y (TSL 1) protected cells from injury by 54.2%, which was significantly higher than salvianolic acid B (35.2%).
    Phytomedicine. 2018 May 15;44:138-147.
    A quality marker study on salvianolic acids for injection.[Pubmed: 29544864 ]
    The quality of Chinese medicine (CM) has being an active and challenging research area for CM. Prof. Chang-Xiao Liu et al first proposed the concept of quality marker (Q-Marker) for the quality evaluation and control on CM. This article describe the exploratory studies of Q-Marker in salvianolic acids for injection (SAI) based on this new concept. This study was designed to screen Q-Marker of SAI and establish its quality control method based on the concept of CM Q-Marker.
    METHODS AND RESULTS:
    Based on the concept of CM Q-Marker, the SAI was investigated for the identification of chemical components and their sources. The pharmacological effects on cerebral ischemia and reperfusion induced injury in rats were also investigated. Furthermore, the target cell extracts and pharmacokinetic studies were conducted to screen Q-Markers. Finally, the fingerprints and determination based on Q-Markers were established to assess the quality of SAI more effectively. Overall, 20 constituents in SAI were identified. It was found that salvianolic acid B (SA-B), rosmarinic acid (RA), lithospermic acid (LA), salvianolic acid D (SA-D) and Salvianolic acid Y (SA-Y) are major chemical components of SAI. Based on chemical components identifications, analysis of their sources, target cell extracts and pharmacokinetic studies, four phenolic acids, namely SA-B, RA, LA and SA-D, were screened and determined as effective Q-Markers of SAI.
    CONCLUSIONS:
    This study demonstrated that the described method is a powerful approach for detecting Q-Markers, which can be used as control index for the quality assessment of CM.
    Glychionide A

    Catalog No: CFN92280
    CAS No: 119152-50-0
    Price: $318/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    3-Epidehydropachymic acid

    Catalog No: CFN92738
    CAS No: 168293-15-0
    Price: $338/5mg
    Glucoliquiritin

    Catalog No: CFN95011
    CAS No: 93446-18-5
    Price: $318/10mg
    Cordifolioside A

    Catalog No: CFN95040
    CAS No: 155179-20-7
    Price: $368/10mg
    Carasiphenol C

    Catalog No: CFN95045
    CAS No: 868168-04-1
    Price: $368/5mg
    Physalin G

    Catalog No: CFN95104
    CAS No: 76045-38-0
    Price: $388/5mg
    Glycinol

    Catalog No: CFN95122
    CAS No: 69393-95-9
    Price: $398/5mg
    Cichoriin

    Catalog No: CFN95196
    CAS No: 531-58-8
    Price: $100/20mg
    4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol

    Catalog No: CFN95200
    CAS No: 913643-31-9
    Price: $368/5mg