Methyl salvionolate A | CAS:1015171-69-3

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Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis.[Pubmed: 18464075]

METHODS AND RESULTS:
During the study of anti-HIV-1 active components of the aqueous extracts of the roots of Salvia yunnanensis, three new derivatives of polyphenols, namely: Methyl salvionolate A (2), ethyl salvianolate A (3) and cis-lithospermic acid (5) were isolated along with two known polyphenols, salvianolic acid A (1) and lithospermic acid (4) their structures were elucidated on the basis of NMR and MS spectral analyses.
CONCLUSIONS:
The anti-HIV-1 activities of the 5 polyphenols were tested for the inhibition of P24 antigen in HIV-1 infected MT-4 cell cultures and HIV-1 replicative enzymes in vitro.

Product Name	Methyl salvionolate A
CAS No.:	1015171-69-3
Catalog No.:	CFN92564
Molecular Formula:	C₂₇H₂₄O₁₀
Molecular Weight:	508.5 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Powder
Targets:	HIV
Source:	The roots of Salvia miltiorrhiza Bge.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
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