Hot Products

Sculponeatin K
Catalog No: CFN98721

Standard reference

Scutebarbatine A
Catalog No: CFN99832

Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.

Scutebarbatine B
Catalog No: CFN97471

Scutebarbatine B shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 uM against K562 cell lines and HL60 cell lines.

Scutellarein
Catalog No: CFN98557

Scutellarein has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities, it can improve neuronal injury, has better protective effect in rat cerebral ischemia. Scutellarein may serve as a SARS-CoV chemical inhibitor, it also exerts strong inhibition towards the tested UDP-glucuronosyltransferase isoforms.

Scutellarein-7-O-glucoside
Catalog No: CFN95082

Scutellarein-7-O-glucoside inhibites MMP-2 activity.

Scutellaric acid
Catalog No: CFN99045

Reference standards.

Scutellarin
Catalog No: CFN99112

Scutellarin has many pharmacological effects, such as antioxidant, antitumor, antiviral, neuroprotection and antiinflammatory activities. It down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.

Scutellarin methylester
Catalog No: CFN90695

Sec-O-Glucosylhamaudol
Catalog No: CFN99743

Sec-O-glucosylhamaudol has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal sec-O-glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.

Secoisolariciresinol
Catalog No: CFN98363

Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes. Secoisolariciresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. (-)-Secoisolariciresinol exerts a suppressive effect on the gain of body weight of mice fed a high-fat diet by inducing gene expression of adiponectin, resulting in the altered expression of various genes related to the synthesis and β-oxidation of fatty acids.