Sauchinone
Catalog No: CFN90153
Sauchinone possesses diverse pharmacological properties, such as hepatoprotective, neuroprotective, anti-inflammatory and anti-tumor effects. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Sauchinone can be used for the prevention of functional β-cell damage, it prevents cytokine-induced NO production, iNOS expression,JAK/STAT activation,and NF-κB activation and inhibition of glucose-stimulated insulin secretion (GSIS).
Schisandrol A
Catalog No: CFN99012
Schisandrol A may be a new promising treatment for neurotoxicity, erectile dysfunction and cardiovascular disease.It can inhibit the activities of Pgp,Beta Amyloid,CYP3A4,cGMP,and NOS, the IC(50) value of CYP3A4 is 32.02 microM.
Schisandrone
Catalog No: CFN92351
Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has protective effects on cells under active oxygen stress state. Schisandrone can significantly decrease phosphorylation levels of Tau protein at 396, 262 sites, and relieve neuronal injury, but the phosphorylation level does not reach a negative cell level; it can suppress the Aβ-induced oxidative stress and inflammatory reaction through influencing NF-κB signaling pathway, exerting its protective effect on Alzheimer disease.
