Hot Products

Resorcinol
Catalog No: CFN99089

Resorcinol is an antiseptic and a disinfectant, and a chemical intermediate for the production of many other pharmaceuticals，is used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

Resveratrol
Catalog No: CFN98791

Resveratrol, a natural polyphenol that possesses anti-oxidant, anti-inflammatory, cardioprotective, blood-sugar-lowering, antiaging, and anti-cancer properties. It has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM, kinases, sirtuins, c-IAP1, c-IAP2, livin and XIAP. Resveratrol regulates gene transcription via activation of the stimulus-regulated protein kinases Raf and ERK and the stimulus-responsive transcription factors TCF and Egr-1.

Resveratroloside
Catalog No: CFN93239

Resveratroloside has cardioprotective effect, it exhibits α-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4. Resveratroloside has anti-inflammatory activity, it shows similar nitric oxide (NO) inhibition potency as that of piceid (the major constituent of P. cuspidatum).

Reticuline
Catalog No: CFN98767

Reticuline is a key compound in the biosynthetic pathway for isoquinoline alkaloids in plants, which include morphine, codeine and berberine. Reticuline possesses potent central nervous system depressant action, it (50-100 mg/kg i.p.) can produce alteration of behaviour pattern, prolongation of pentobarbital-induced sleep, reduction in motor coordination and D-amphetamine-induced hypermotility and suppression of the conditioned avoidance response. (S)-Reticuline can elicit vasorelaxation probably due to the blockade of the L-type voltage-dependent Ca(2+) current in rat aorta, the effect may contribute to the potential cardioprotective efficacy of (S)-reticuline.

Retinoic acid
Catalog No: CFN90026

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. It also helps repair Smad3/TGF-β1-induced lung damage in hyperoxic mice.

Retronecine
Catalog No: CFN00322

Retronecine acts as the better competitor for the competitive inhibition of antibodies to Retronecine. Retronecine can be metabolized to form DHP by rat liver microsomal enzymes and interacts with DNA to produce DHP-DNA adducts and Retronecine N-oxide undergoes the biotransformation to the parent compound, Retronecine.

Retrorsine
Catalog No: CFN00407

Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells.OCT1 mediates the liver-specific uptake of Retrorsine, and plays an important role in Retrorsine-induced hepatotoxicity together with CYP3A4. Consequently, the OCT1 inhibitors could be applied to protect the liver from the toxicity of Retrorsine.

Retusin
Catalog No: CFN89520

Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis.

Retusine
Catalog No: CFN00411

Retusine has edema inhibition capacity, could be related to a reduction of the prostaglandin production. Retusine shows activity against the Gram-positive bacteria C. diphtheria and S. aureus.

Reutericyclin
Catalog No: CFN00135

Reutericyclin is a unique antimicrobial tetramic acid produced by some strains of Lactobacillus reuteri, dissipation of the membrane potential by active Reutericyclins correlated with inhibition of macromolecular synthesis in cells. Reutericyclin and nisin exhibit divergent effects on heat- and pressure-induced spore inactivation and membrane fluidity. All reutericyclins can inhibit the growth of clinical isolates of drug-resistant Staphylococcus aureus, which exemplify the prospect of developing reutericyclins as new topical antibiotics.