Polygalasaponin V
Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Microbiol Biotechnol.2023, 33(10):1317-1328.
Natural Product Communications2020, doi: 10.1177.
Nutrients.2022, 14(23):4997.
J Nat Prod.2021, 84(9):2544-2553.
Pharmaceuticals (Basel).2024, 17(3):352.
Arch Biochem Biophys.2020, 687:108363.
Molecules.2015, 20(10):19172-88
Int J Mol Sci.2024, 25(19):10660.
Separations2021, 8(6),80.
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CHEMICAL & PHARMACEUTICAL BULLETIN, 1995, 43(1):115-120.
Studies on the Constituents of Polygala japonica HOUTT. I. Structures of Polygalasaponins I-X.[Reference:
WebLink]
METHODS AND RESULTS:
Ten new oleanane-type saponins, polygalasaponin I, polygalasaponin II, polygalasaponin III , polygalasaponin IV ,Polygalasaponin V, Polygalasaponin VI , Polygalasaponin VII ,Polygalasaponin VIII , polygalasaponin IX, polygalasaponin X, along with two known saponins, bayogenin-3-O-beta-D-glucopyranoside and lobatoside B were isolated from the aerial part of Polygala japonica Houtt.
CONCLUSIONS:
The structures of these compounds were established on the basis of spectroscopic and chemical evidence.
