Hot Products

Scoparone
Catalog No: CFN99314

Scoparone is a phytoalexin with antifungal,anticoagulant, antianginal, hypolipidemic, vasorelaxant, immunosuppression, hepatoprotective,anti-allergic,antioxidant, and anti-inflammatory actions, it is used for the traditional treatment of neonatal jaundice. It inhibited the activities of PPARγ, STAT3, NADPH-oxidase 1, and the expression of ERK,NF-kB, JNK,PI3K. It augmented the expression of SOD1 and CAT.

Scopine
Catalog No: CFN00226

Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist. It is a potential brain-targeting moiety for enhancing the brain uptake efficiency of chlorambucil, and used in the treatment of acute circulatory shock.

Scopolamine
Catalog No: CFN98200

Scopolamine is a high affinity (nM) muscarinic antagonist. 5-HT3 receptor-responses are reversibly inhibited by Scopolamine with an IC50 of 2.09 μM. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. It also can produce rapid and significant symptom improvement in patients with depression.

Scopolamine butylbromide
Catalog No: CFN98158

Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM, it possesses anticholinergic, and anti-tumor effects, it used as an abdominal-specific antispasmodic agent. Scopolamine butylbromide is effective in preventing succinylcholine-induced bradycardia in infants and children.

Scopolamine hydrobromide
Catalog No: CFN99709

Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 nM, it also reversibly inhibited the 5-HT3 receptor-responses with an IC50 of 2.09 μM. Sscopolamine hydrobromide nasal gel is a safe and promising therapeutic alternative to existing medications for motion sickness, it and NaHCO3 can be used to treat tetrodotoxin (TTX) poisoning.

Scopoletin
Catalog No: CFN97494

Scopoletin exhibits antifungal, anti-allergic, anti-aging, and hypouricemic activities, it exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways. Scopoletin can ameliorate alcohol-induced hepatic lipid accumulation by modulating AMPK-SREBP pathway-mediated lipogenesis in mice fed a high-fat diet.

Scopolin
Catalog No: CFN98887

Scopolin exhibits significant and dose-related antinociceptive effects, it is a potential acetylcholinesterase (AChE) inhibitor. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, it may be a potent agent for angiogenesis related diseases.Scopolin and related coumarins has fungitoxic effect on Sclerotinia sclerotiorum, which is a way to overcome sunflower head rot.

Scopoline
Catalog No: CFN00228

Scopoline, tropinol, ecgonine, and granatoline derivatives are therapeutic agents of the pyrrole and pyridine group. Scopoline has fungitoxic effects, it is inhibitory to Sclerotinia at similar doses to scopoletin; as scopolin is known to be less phytotoxic than ayapin and scopoletin, its accumulation may well confer head rot resistance with minimal plant damage and might be one of the bases for resistance to Sclerotinia.

Scoulerine
Catalog No: CFN96330

Scoulerine shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively. It shows antiplasmodial activity with IC(50) values of 5.4uM and 3.1uM against the antifolate sensitive and the multidrug resistant P. falciparum strains: TM4/8.2 and K1CB1, respectively.

Sculponeatin A
Catalog No: CFN97414

Sculponeatin A is a natural product from Rabdosia amethystoides.