Hot Products

Euphorbia factor L8
Catalog No: CFN92886

Reference standards.

Euphorbia factor L9
Catalog No: CFN92887

Reference standards.

Euphorbiasteroid
Catalog No: CFN90641

Euphorbiasteroid has anti-obesity activities, it inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway. Euphorbiasteroid could be a transport substrate for P-gp that can effectively inhibit P-gp-mediated drug transport and reverse resistance to anticancer drugs in MES-SA/Dx5 cells; it induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner.

Europine
Catalog No: CFN00264

Europine shows both antifungal and insect antifeedant activity.

Europine N-oxide
Catalog No: CFN00265

Supinine, lasiocarpine-N-oxide and Europine N-oxide exhibit virucidal activity to Poliomyelitis, Coxsackie, Semliki forest, Vesicular stomatitis and Herpes simplex at the concentration of 5, 10 and 20 mu g/ml respectively.

Eurycarpin A
Catalog No: CFN97806

Standard reference

Eurycomalactone
Catalog No: CFN92129

Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)].

Eurycomalide A
Catalog No: CFN92748

Standard reference

Eurycomanone
Catalog No: CFN92008

Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.

Euscaphic acid
Catalog No: CFN98888

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations. Euscaphic acid induces death by activation of caspase-3, dependent apoptotic pathway. Euscaphic acid and tormentic acid have inhibitory effect on high fat diet-induced obesity in the rat. Euscaphic acid also has anti-contraction effects on rat’s aortic smooth muscle.