Hot Products

Galangin 3-methyl ether
Catalog No: CFN92776

Galangin-3-methylether has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. 3-Methylethergalangin has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.

Galanolactone
Catalog No: CFN99258

Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. Galanolactone exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes.Galanolactone also shows cytotoxic activity .

Galantamine
Catalog No: CFN90743

Galantamine is an acetylcholinesterase inhibitor, can reduce brain damage induced by hypoxia-ischemia. It may be a candidate drug for treating relapses of METH-seeking behavior.

Galantamine hydrobromide
Catalog No: CFN90744

Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.

Gallic acid
Catalog No: CFN99624

Gallic acid, is a histone acetyltransferase inhibitor and a potent inhibitor of brush border sucrase and other disaccharidases, which has powerful antioxidant, anti-tumor, and anti-tyrosinase activities. It can potentially interfere with the digestive functions of the intestine. It can efficiently block neuronal cell death by downregulating the expression of cytokines and the in vivo levels of NF-κB acetylation, is a possible therapeutic approach for alleviating the inflammatory progression of Alzheimer disease.

Gallic aldehyde
Catalog No: CFN90983

Gallic aldehyde shows potent antiviral activity against HSV-1.

Gallocatechin gallate
Catalog No: CFN96488

Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabetic effects by increasing sensitivity of insulin. Gallocatechin gallate can decrease osteoclastogenesis at 20 microM, it has positive effects on bone metabolism through a double process of promoting osteoblastic activity and inhibiting osteoclast differentiations.

Galloylpaeoniflorin
Catalog No: CFN90831

Galloylpaeoniflorin exhibits anticomplement effects, it reveals a more pronounced radical scavenging effect than a-tocopherol. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. Galloylpaeoniflorin exhibits good activity on acute lung injury.

Gamabufotalin
Catalog No: CFN90212

Gamabufotalin has been used for treatment of COX-2-mediated diseases and cancer therapy, it triggers c-Myc degradation via induction of WWP2 in multiple myeloma(MM) cells. Gamabufotalin strongly inhibit cancer cell growth and inflammatory response, it inhibits angiogenesis by inhibiting the activation of VEGFR-2 signaling pathways and could be a potential candidate in angiogenesis-related disease therapy.

Gambogenic acid
Catalog No: CFN92097

Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways.