Hot Products

Eupalinolide A
Catalog No: CFN90381

Eupalinolide A and Eupalinolide B induce the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90. They could be beneficial for use in cosmetics and medicines as a consequence of their inhibitory action on UV-induced skin damage and melanin production.

Eupalinolide B
Catalog No: CFN90382

Eupalinolide B demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.Eupalinolide B and Eupalinolide A induce the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90, they could be beneficial for use in cosmetics and medicines as a consequence of their inhibitory action on UV-induced skin damage and melanin production.

Eupalinolide K
Catalog No: CFN99435

Reference standards.

Eupalinolide O
Catalog No: CFN91839

Eupalinolide O shows significant anticancer activity, it induces cell cycle arrest and apoptosis in human MDA-MB-468 breast cancer cells.

Eupalitin
Catalog No: CFN70334

Eupalitin has anti-cancer activity, it induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase-3 activity.

Euparin
Catalog No: CFN96884

Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to cells up to the first twenty minutes after infection.

Eupatilin
Catalog No: CFN90190

Eupatilin has anti-inflammatory, and anti-tumor properties, it inhibits the MKN-1 gastric cancer cell proliferation via activation of caspase-3 and the metastatic potential of gastric cancer cells via down-regulation of NF-κB activity followed by reduction of pro-inflammatory cytokine-mediated MMPs expressions. Eupatilin inhibits the signalling of MAPK, IKK, NF-κB and eotaxin-1 in bronchial epithelial cells, leading to inhibition of eosinophil migration. Eupatilin is also a promising therapeutic agent against acute ischemia-induced renal damage, it significantly increases the levels of heat shock protein 70 and B-cell lymphoma protein, and it attenuates inducible nitric oxide synthase, Bcl-2-associated X protein, and caspase-3 levels.

Eupatoletin
Catalog No: CFN92698

Reference standards.

Eupatolide
Catalog No: CFN89045

Eupatolide has anti-inflammatory activity, it inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6. It can suppress PDGF-induced proliferation and migration of VSMC through HO-1 induction via ROS-Nrf2 pathway and may be a potential HO-1 inducer for preventing or treating vascular diseases. Eupatolide exhibits potent cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cancer cell lines, with IC50 values ranging from 1.57 to 22.58 uM; it sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression, it is a valuable compound to overcome TRAIL resistance in breast cancer cells.

Eupatorin
Catalog No: CFN97418

Eupatorin has antiproliferative and antiangiogenic effects, it emerges as a promising agent in anticancer research.Eupatorin-induced cell death is mediated by both the extrinsic and the intrinsic apoptotic pathways and through a mechanism dependent on reactive oxygen species generation. Eupatorin also has meaningful anti-inflammatory property which may be utilized in the development of novel anti-inflammatory treatments.