Ferruginol
Catalog No: CFN92178
Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi.
Ferulic acid
Catalog No: CFN99158
Ferulic acid is an antioxidant found naturally in plant cell walls , shows antioxidant activity in parallel with their radical scavenging activity, it has been approved in certain countries as food additive to prevent lipid peroxidation. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, anti- diabetic, and anti-cancer activities; it also protects against coronary disease, lowers cholesterol and increases sperm viability.
Ficusin A
Catalog No: CFN99817
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the translocation and activation of GLUT4 in the adipose tissue, suggests that ficusin improves the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitusl.
Fisetin
Catalog No: CFN98176
Fisetin is an antimetastatic,antifungal, anti-inflammatory, antioxidant flavonoid, it has beneficial effect on periodontal disease, may via inhibiting MAPK activation and COX-2 expression without affecting cell viability. Fisetin can ameliorate photodamage by suppressing the mitogen-activated protein Kinase/Matrix metalloproteinase pathway and nuclear factor-κB pathways. Fisetin suppresses the accumulation of intracellular lipids by inhibiting GLUT4-mediated glucose uptake through inhibition of the mTOR-C/EBPα signaling in 3T3-L1 cells.
Flavoglaucin
Catalog No: CFN96893
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammatory effects, it shows inhibitory effects on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Flavoglaucin exhibits a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with theIC(50) value of 11.3 microM.
Flavokawain B
Catalog No: CFN92661
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. Flavokawain B has potent anti-inflammatory, and anti-cancer activities, it can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.
