Fraxetin
Catalog No: CFN99113
Fraxetin has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
Fraxin
Catalog No: CFN99747
Fraxin possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis. Fraxin enhances urate excretion partly by inhibiting mURAT1 or mGLUT9 in kidney of hyperuricemic mice.
Fraxinellone
Catalog No: CFN99782
Fraxinellone is a selective blocker of voltage-dependent Ca2+ channel, which possesses antimicrobial, anti-inflammatory, neuroprotective and vasorelaxing activities, Fraxinellone exhibits a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. It inhibited the production of iNOS, COX-2, NF-kappa B, and PGE(2).
Friedelin
Catalog No: CFN98936
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.Friedelin rich fraction (IND-HE) shows estrogenic activity as indicated by vaginal cornification, increase in uterine weight and rise in serum estrogen. Friedelin may be beneficial to mimic insulin action that would be useful in the treatment of diabetes type 2 patients.
Fructose
Catalog No: CFN98121
Fructose is a simple ketonic monosaccharide found in many plants. Dietary fructose can specifically increase hepatic de novo lipogenesis (DNL), promote dyslipidemia, decreases insulin sensitivity, and increase visceral adiposity in overweight/obese adults; it also can reduce circulating insulin and leptin, attenuate postprandial suppression of ghrelin, and increase triglycerides in women.
Fucosterol
Catalog No: CFN91947
Fucosterol possesses anti-oxidant, hepatoprotective, cytotoxic, antihistaminic, anticholinergic and antiviral activities. Fucosterol exhibits anti-inflammatory activity which might attribute to inhibition of NO and ROS generation and suppression of the NF-κB pathway. Fucosterol also has anti-diabetic activity in vivo, it exhibits an inhibition of sorbitol accumulations in the lenses and causes an inhibition of blood glucose level and glycogen degradation. Fucosterol is a dual-LXR agonist that regulates the expression of key genes in cholesterol homeostasis in multiple cell lines without inducing hepatic triglyceride accumulation; it could as an anti-obesity agent, it can inhibit expression of PPARγ and C/EBPα, resulting in a decrease of lipid accumulation in 3T3-L1 pre-adipocytes.
