Dimethylcurcumin

Dimethylcurcumin
Product Name Dimethylcurcumin
CAS No.: 52328-98-0
Catalog No.: CFN90607
Molecular Formula: C23H24O6
Molecular Weight: 396.43 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Targets: Androgen Receptor
Source: The rhizomes of Curcuma rcenyujin.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $218/20mg
Dimethylcurcumin is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Integrative Medicine Research2024, 13(1):101025.
  • Front Pharmacol.2019, 10:1226
  • J Ethnopharmacol.2024, 324:117775.
  • Molecules.2023, 28(9):3685.
  • Indian J. of Experimental Bio.2020, 9(58).
  • Carbohydrate Polymer Technologies & App.2021, 2:100049.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1124:323-330
  • Nat Plants.2016, 3:16205
  • Synthetic and Systems Biotechnology2023, j.synbio.
  • Front Pharmacol.2022, 13:870553.
  • 1,5-Epoxy-3S-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane

    Catalog No: CFN95858
    CAS No: 182369-54-6
    Price: $368/5mg
    4'-O-Methylnyasol

    Catalog No: CFN89281
    CAS No: 79004-25-4
    Price: $318/5mg
    3'-Methoxynyasin

    Catalog No: CFN95870
    CAS No: 1685246-20-1
    Price: $318/5mg
    Nyasicol

    Catalog No: CFN99213
    CAS No: 111518-95-7
    Price: Inquiry(manager@chemfaces.com)
    Nyasicol 1,2-acetonide

    Catalog No: CFN96568
    CAS No: 1432057-64-1
    Price: Inquiry(manager@chemfaces.com)
    Nyasicoside

    Catalog No: CFN99212
    CAS No: 111518-94-6
    Price: Inquiry(manager@chemfaces.com)
    Pilosidine

    Catalog No: CFN95110
    CAS No: 229971-57-7
    Price: $413/5mg
    4-(3,5-Dihydroxy-7-(4-hydroxy-3-methoxyphenyl)heptyl)benzene-1,2-diol

    Catalog No: CFN95879
    CAS No: 884495-94-7
    Price: $318/10mg
    Octahydrocurcumin

    Catalog No: CFN90584
    CAS No: 36062-07-4
    Price: $388/20mg
    5'-Hydroxyoctahydrocurcumin

    Catalog No: CFN95880
    CAS No: N/A
    Price: $318/10mg
    Mol Nutr Food Res. 2008 Sep;52(9):1005-9.
    Curcumin in cancer management: recent results of analogue design and clinical studies and desirable future research.[Pubmed: 18186103]

    METHODS AND RESULTS:
    The ability of the curry constituent curcumin to delay the onset of cancer has been the topic of extensive research for many years. Abundant literature is devoted to mechanisms by which curcumin may mediate this activity. These insights have prompted investigations in which curcumin as lead molecule serves as a scaffold for synthetic chemical attempts to optimize pharmacological potency. Among the published analogues with notable efficacy are Dimethylcurcumin, 1,5-bis(3-pyridyl)-1,4-pentadien-3-one and 3,5-bis-(2-fluorobenzylidene)-piperidinium-4-one acetate. Results of a small number of clinical pilot studies conducted with curcumin at doses of up to 12 g suggest tentatively that it is safe in humans.
    CONCLUSIONS:
    Prevention of adenoma recurrence constitutes a clinical paradigm worthy of further investigation for curcumin. Future clinical study should include measurement of mechanism-based pharmacodynamic parameters.
    3''-O-Galloylmyricitrin

    Catalog No: CFN95057
    CAS No: 143202-36-2
    Price: $333/5mg
    Microgrewiapine A

    Catalog No: CFN95125
    CAS No: 1420777-30-5
    Price: $413/5mg
    Peiioside B

    Catalog No: CFN95336
    CAS No: 1610618-91-1
    Price: $318/5mg
    New compound 8

    Catalog No: CFN95341
    CAS No: N/A
    Price: $318/5mg
    Hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95367
    CAS No: 76873-99-9
    Price: $318/10mg
    3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside

    Catalog No: CFN95375
    CAS No: 352280-34-3
    Price: $413/5mg
    Meliotocarpan D

    Catalog No: CFN95401
    CAS No: 83013-81-4
    Price: $413/5mg
    7-Oxodehydroabietic acid

    Catalog No: CFN95411
    CAS No: 18684-55-4
    Price: $318/5mg
    Giganteone A

    Catalog No: CFN95481
    CAS No: 460337-13-7
    Price: $318/5mg
    Octyl 3-(4-hydroxyphenyl)prop-2-enoate

    Catalog No: CFN95563
    CAS No: N/A
    Price: $318/5mg