Dimeric coniferyl acetate

Dimeric coniferyl acetate
Product Name Dimeric coniferyl acetate
CAS No.: 184046-40-0
Catalog No.: CFN99853
Molecular Formula: C24H26O8
Molecular Weight: 442.5 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: NO
Source: The herbs of Jatropha integerrima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibitory effects on the nitric oxide production in lipopolysaccharide activated C57BL6/J mouse macrophages.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Appl. Sci.2020, 10(23), 8729
  • Phytochem Anal.2021, 32(6):970-981.
  • J. Mater. Life Sci.2024, 3:2:78-87
  • J Med Food.2019, 22(10):1067-1077
  • PLoS One.2018, 13(11):e0208055
  • Molecules.2023, 28(17):6315.
  • Nat Prod Sci.2016, 22(2)
  • Wageningen University & Research2018, January 2018
  • Chem Biodivers.2023, 20(12):e202301461.
  • Mol Med Rep.2022, 26(4):299.
  • 3,4-O-dimethylcedrusin

    Catalog No: CFN95026
    CAS No: 166021-14-3
    Price: $388/10mg
    Massonianoside A

    Catalog No: CFN95708
    CAS No: 623945-11-9
    Price: $318/5mg
    Massonianoside B

    Catalog No: CFN99869
    CAS No: 188300-19-8
    Price: Inquiry(manager@chemfaces.com)
    Icariside E4

    Catalog No: CFN95639
    CAS No: 126253-42-7
    Price: $318/10mg
    Massonianoside D

    Catalog No: CFN95500
    CAS No: 85115-04-4
    Price: $318/10mg
    Urolignoside

    Catalog No: CFN96465
    CAS No: 131723-83-6
    Price: $318/10mg
    (7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-beta-D-glucoside

    Catalog No: CFN95755
    CAS No: 351346-10-6
    Price: $368/5mg
    Hierochin D

    Catalog No: CFN99663
    CAS No: 155759-02-7
    Price: $368/5mg
    (2R,3S)-Dihydrodehydroconiferyl alcohol

    Catalog No: CFN92904
    CAS No: 126253-41-6
    Price: Inquiry(manager@chemfaces.com)
    Dihydrodehydrodiconiferyl alcohol

    Catalog No: CFN98342
    CAS No: 28199-69-1
    Price: Inquiry(manager@chemfaces.com)
    Journal of Traditional Medicines, 2003, 20: 22-9.
    Inhibitors of nitric oxide (NO) production in murine macrophage-like J774.1 cells from Brazilian propolis[Reference: WebLink]

    METHODS AND RESULTS:
    Water and MeOH extracts of Brazilian propolis showed dose-dependent inhibition toward nitric oxide (NO) production in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. From the water extract, 17 phenolic compounds were isolated and among them 15 are new for the water extract of propolis. Moreover, methyl ρ-hydroxydihydrocinnamate (9) and 1-(4-hydroxyphenyl)butane-1,3-dione (11) were isolated, for the first time, from propolis.
    CONCLUSIONS:
    Labdane-type diterpenes, flavonoids and some phenolic compounds possessed potent NO inhibitory activity. Coniferyl aldehyde (23) and Dimeric coniferyl acetate (33) showed the strongest NO inhibition with IC_50 values of 18.0 and 27.1 μM, respectively, which were stronger than the positive control, N^G-monomethyl-L-arginine (L-NMMA ; IC_50, 44.5 μM).
    J Asian Nat Prod Res. 2014 Jan;16(1):1-10.
    Five new compounds from Rhododendron mariae Hance.[Pubmed: 24320934 ]

    METHODS AND RESULTS:
    Five new compounds (-)-(7R,8S,7'R,8'S)-4,9,4',9'-tetrahydroxy-3,3'-dimethoxy-7,7'-epoxylignan 9-O-β-d-xylopyranoside (1), (-)-(7'R,8'S)-5'-methoxyl(Dimeric coniferyl acetate) (2), (+)-(1R,2S)-1,2-bis(4-hydroxy-3-methoxyphenyl)-3-acetyl-1,3-propanediol (3), (-)-3-((2R,3R)-2-ethoxy-3-(hydroxymethyl)-7-methoxy-2,3-dihydrobenzofuran-5-yl)propan-1-ol (4), and (+)-3-((2S,3S)-2-ethoxy-3-(hydroxymethyl)-7-methoxy-2,3-dihydrobenzofuran-5-yl)propan-1-ol (5), together with 12 known compounds, were isolated from an ethanol extract of the dried stems of Rhododendron mariae Hance. Their structures were elucidated by NMR, HR-MS, CD, ORD experiments and chemical methods.
    CONCLUSIONS:
    Compounds 2, 3, 6, and 17 exhibited significant inhibitory effects on the nitric oxide production in lipopolysaccharide activated C57BL6/J mouse macrophages.
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $318/5mg
    Torosachrysone 8-O-beta-gentiobioside

    Catalog No: CFN95131
    CAS No: 94356-13-5
    Price: $318/5mg
    N-Methylcorydalmine

    Catalog No: CFN95204
    CAS No: 81010-29-9
    Price: $398/5mg
    Sphenanlignan

    Catalog No: CFN95245
    CAS No: 866347-36-6
    Price: $318/5mg
    New compound 6

    Catalog No: CFN95259
    CAS No: N/A
    Price: $413/5mg
    9-Hydroxy-O-senecioyl-8,9-dihydrooroselol

    Catalog No: CFN95274
    CAS No: 31456-63-0
    Price: $318/5mg
    Fuzitine

    Catalog No: CFN95337
    CAS No: 142287-96-5
    Price: $318/5mg
    2,3-Dehydrosilychristin

    Catalog No: CFN95370
    CAS No: 57499-41-9
    Price: $318/5mg
    8-Epiloganin

    Catalog No: CFN95478
    CAS No: 79172-04-6
    Price: $318/20mg
    Bayin

    Catalog No: CFN95539
    CAS No: 3681-96-7
    Price: $318/5mg