Carvacryl acetate
Catalog No: CFN70485
Carvacryl acetate, a TRPA1 receptor agonist, which has anti-inflammatory, antioxidant, anxiolytic-like, and anti-epilepsy activities. It exhibited anti-inflammatory activity in mice by reducing inflammatory mediators, neutrophil migration and cytokine concentration, and anti-nociceptive activity due to the involvement of capsaicin and glutamate pathways. Carvacryl acetate seems to have an anxiolytic-like effect, probably due to GABAergic agonist action, without psychomotor side effects. Carvacryl acetate also shows neuropharmacological effects on δ-aminolevulinic dehydratase, Na+, K+-ATPase activities and amino acids levels in mice hippocampus after seizures. Carvacryl acetate at 6.25 μg/mL has antischistosomal activity.
Caryophyllene oxide
Catalog No: CFN99239
Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with antifungal, acaricidal, anti-inflammatory, anti-carcinogenic, significant central as well as peripheral analgesic and skin penetration enhancing properties. Caryophyllene Oxide and lupenone have synergistic effect against Trypanosoma cruzi. It inhibited growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways, ROS-mediated MAPKs activation, and via modulation of 15-LOX.
Catalpol
Catalog No: CFN98251
Catalpol is a kind of enzyme inhibitors, it has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.Catalpol regulates cholinergic nerve system function through effect on choline acetyl-transferase not M receptor affinity, it has a wide spectrum of targets including Bcl-2 , PI3K, Akt-eNOS, caspase.
Catalposide
Catalog No: CFN97148
Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties. Catalposide is a potent inducer of HO-1 and HO-1 induction is responsible for the catalposide-mediated cytoprotection against oxidative damage.Catalposide is a natural agonistic ligand of peroxisome proliferator-activated receptor-α, is hypolipidemic by activation of PPARαvia a ligand-mediated mechanism that modulates the expression of in lipid metabolism genes in hepatocytes.
Catechin
Catalog No: CFN99646
Catechin, a cyclooxygenase-1 (COX-1) inhibitor with an IC50 of 1.4 μM, which has antiangiogenic, antitumor, antioxidant, UV-protective, anti-aging, phytotoxic, antimicrobial, and antiviral effects. Catechin shows its potential as biobased active packaging for fatty food, and exerts cardioprotection through treating many kinds of angiocardiopathy.
