Pieceid-2''-O-gallate
Pieceid-2''-O-gallate has antioxidant activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Tumour Biol.2015, 36(9):7027-34
Drug Chem Toxicol.2020, 1-14.
J of l. Chroma.&Related Tech2020, 43(11-12):414-423.
J Formos Med Assoc.2020, S0929-6646(20)30425-3
Korean J of Medicinal Crop Science2018, 220-226
J Pharm Pharmacol.2022, rgac033.
Oncotarget.2017, 8(53):90925-90947
Int J Mol Sci.2020, 21(22):8816.
Evid Based Complement Alternat Med.2017, 2017:7383104
Environ Toxicol Pharmacol.2019, 66:109-115
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Phytochemistry, 2003, 64(3):759-763.
Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities.[Reference:
WebLink]
METHODS AND RESULTS:
Two stilbene glycosides, Pieceid-2''-O-gallate and pieceid-2″-O-coumarate, were isolated from the MeOH extract of the roots of Pleuropterus ciliinervis Nakai (Polygonaceae), together with two known compounds, resveratrol and pieceid. Their structures were determined spectroscopically, particularly by 2D NMR spectroscopic analysis. The antioxidant activities of stilbenes isolated were determined in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide radicals and by determining their lipid peroxidation inhibitory activities. Among the compounds isolated, pieceid-2″-O-gallate had the most potent inhibitory scavenging effect on DPPH, superoxide radicals and upon lipid peroxidation inhibition with IC50 values of 16.5, 23.9 and 5.1 μM, respectively.
CONCLUSIONS:
Two stilbene glycisides, (E)-pieceid-2″-O-gallate and (E)-pieceid 2″-O-cumarate, were isolated from the roots of P. ciliinervis, together with resveratrol and pieceid. They showed antioxidant activities.
Química Nova,2014, 37(9):1465-1468.
Separation and purification of three stilbenes from the radix of Polygonum cillinerve (Nakai) Ohwl by macroporous resin column chromatography combined with high-speed counter-current chromatography.[Reference:
WebLink]
Recebido em 26/03/2014; aceito em 08/07/2014; publicado na web em 22/09/2014 An effective method for the rapid separation and purification of three stilbenes from the radix of Polygonum cillinerve (Nakai) Ohwl by macroporous resin column chromatography combined with high-speed counter-current chromatography (HSCCC) was successfully established.
METHODS AND RESULTS:
In the present study, a two-phase solvent system composed of chloroform-n-butanol-methanol-water (4:1:4:2, v/v/v/v) was used for HSCCC separation. A one-step separation in 4 h from 150 mg of crude extract produced 26.3 mg of trans-resveratrol-3-O-glucoside, 42.0 mg of Pieceid-2''-O-gallate, and 17.9 mg of trans-resveratrol with purities of 99.1%, 97.8%, and 99.4%, respectively, as determined by high-performance liquid chromatography (HPLC).
CONCLUSIONS:
The chemical structures of these compounds were identified by nuclear magnetic resonance (NMR) spectroscopy.
