Rhaponticin 6''-O-gallate
Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Int J Mol Med.2019, 43(6):2516-2522
RSC Adv.2018, 32621-32636
Comparative Clinical Pathology 2021, 30:961-971.
Journal of Third Military Medical University2019, 41(2):110-115
Food Chem Toxicol.2023, 176:113785.
Int J Mol Sci.2024, 25(6):3390.
Int Immunopharmacol.2020, 90:107268.
Nat Commun.2019, 10(1):5169
Korean Journal of Medicinal Crop Science2018, 26(5):382-390
Food Res Int.2018, 106:909-919
Related and Featured Products
Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.[Pubmed:
10714491 ]
METHODS AND RESULTS:
Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
CONCLUSIONS:
The oxygen functions (-OH,-OCH3) at the benzene ring were found to be essential to show the activity. Whereas, the glucoside moiety reduced the activity, while the alpha,beta-double bond did not affect the activity. Furthermore, the active stilbenes (rhapontigenin, piceatannol, resveratrol) inhibited iNOS induction.
Macrophylloside D
Catalog No: CFN95113
CAS No: 179457-69-3
Price: $318/10mg
3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin
Catalog No: CFN95154
CAS No: 148210-00-8
Price: $413/5mg
(3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol
Catalog No: CFN95195
CAS No: 87095-75-8
Price: $318/5mg
N1,N5,N10-(Z)-tri-p-coumaroylspermidine
Catalog No: CFN95253
CAS No: 131086-78-7
Price: $238/5mg
Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
Catalog No: CFN95276
CAS No: 71781-79-8
Price: $318/10mg
Isocucurbitacin D
Catalog No: CFN95326
CAS No: 68422-20-8
Price: $318/5mg
Dipsacus saponin X
Catalog No: CFN95359
CAS No: 146100-01-8
Price: $318/20mg
3'-Hydroxy-2,4,5-trimethoxydalbergiquinol
Catalog No: CFN95410
CAS No: N/A
Price: $413/5mg
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene
Catalog No: CFN95428
CAS No: 1608462-12-9
Price: $318/10mg
Gambogic acid A
Catalog No: CFN95458
CAS No: 1592842-93-7
Price: $318/5mg
