Rhaponticin 2''-O-gallate

Rhaponticin 2''-O-gallate
Product Name Rhaponticin 2''-O-gallate
CAS No.: 94356-24-8
Catalog No.: CFN91100
Molecular Formula: C28H28O13
Molecular Weight: 572.51 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Targets: NO
Source: The roots of Rumex obtusifolius L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $288/5mg
Rhaponticin 2''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Sci Rep.2015, 5:13194
  • Int J Mol Sci.2018, 19(2)
  • Int J Oncol.2019, 55(1):320-330
  • Sci Rep.2019, 9(1):18080
  • Antimicrob Agents Chemother.2020, AAC.01921-20.
  • Phytother Res.2019, 33(5):1490-1500
  • Biochemistry.2018, 57(40):5886-5896
  • Neurochem Int.2018, 121:114-124
  • Int J Mol Sci.2019, 20(21):E5488
  • Food Chem.2019, 274:345-350
  • Arundinin

    Catalog No: CFN91179
    CAS No: 148225-38-1
    Price: $388/5mg
    Resveratrol

    Catalog No: CFN98791
    CAS No: 501-36-0
    Price: $30/20mg
    Triacetylresveratrol

    Catalog No: CFN90895
    CAS No: 42206-94-0
    Price: $30/20mg
    Polydatin

    Catalog No: CFN99159
    CAS No: 27208-80-6
    Price: $30/20mg
    Pieceid-2''-O-gallate

    Catalog No: CFN95226
    CAS No: 105304-51-6
    Price: $318/10mg
    Dihydroresveratrol

    Catalog No: CFN98987
    CAS No: 58436-28-5
    Price: $288/20mg
    Dihydroresveratrol 3-O-glucoside

    Catalog No: CFN99021
    CAS No: 100432-87-9
    Price: Inquiry(manager@chemfaces.com)
    Desoxyrhapontigenin

    Catalog No: CFN90854
    CAS No: 33626-08-3
    Price: $318/10mg
    Desoxyrhaponticin

    Catalog No: CFN90911
    CAS No: 30197-14-9
    Price: $238/20mg
    Rhaponticin 6''-O-gallate

    Catalog No: CFN91099
    CAS No: 94356-23-7
    Price: $268/5mg
    Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.
    Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.[Pubmed: 10714491 ]

    METHODS AND RESULTS:
    Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (Rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
    CONCLUSIONS:
    The oxygen functions (-OH,-OCH3) at the benzene ring were found to be essential to show the activity. Whereas, the glucoside moiety reduced the activity, while the alpha,beta-double bond did not affect the activity. Furthermore, the active stilbenes (rhapontigenin, piceatannol, resveratrol) inhibited iNOS induction.
    Naringin 4'-glucoside

    Catalog No: CFN95014
    CAS No: 17257-21-5
    Price: $338/5mg
    Momordicine II

    Catalog No: CFN95167
    CAS No: 91590-75-9
    Price: $318/10mg
    Dichotomine B

    Catalog No: CFN95193
    CAS No: 755036-41-0
    Price: $463/5mg
    6'-Feruloylnodakenin

    Catalog No: CFN95202
    CAS No: 131623-14-8
    Price: $318/10mg
    4'-O-Methyllucenin II (Diosmetin 6,8-di-C-glucoside)

    Catalog No: CFN95344
    CAS No: 98813-28-6
    Price: $318/10mg
    Isospinosin

    Catalog No: CFN95350
    CAS No: 89701-83-7
    Price: $318/5mg
    Isosilychristin

    Catalog No: CFN95369
    CAS No: 77182-66-2
    Price: $318/5mg
    5,6,7,3',4',5'-Hexamethoxyflavanone

    Catalog No: CFN95376
    CAS No: 74064-17-8
    Price: $318/10mg
    3'-Hydroxy-2,4,5-trimethoxydalbergiquinol

    Catalog No: CFN95410
    CAS No: N/A
    Price: $413/5mg
    Jacquilenin

    Catalog No: CFN95434
    CAS No: 7726-34-3
    Price: $318/5mg