Magnaldehyde B

Magnaldehyde B
Product Name Magnaldehyde B
CAS No.: 92829-72-6
Catalog No.: CFN95075
Molecular Formula: C18H16O3
Molecular Weight: 280.3 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The barks of Magnolia officinalis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/5mg
Magnaldehyde B is a natural lipase inhibitor(IC50= 96.96 uM). Magnaldehyde B can inhibit the proliferation of tumor cells, and might be an anti-tumoric agent.
Inquire / Order:
Technical Inquiries:
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Biomed Pharmacother.2021, 139:111585.
  • J Biochem Mol Toxicol.2021, 35(5):e22731.
  • Phytochem Anal.2013, 24(5):493-503
  • BMC Complement Altern Med.2016, 16:213
  • Molecules.2023, 28(19):6775.
  • Nutrients.2019, 11(4):E936
  • Int J Biol Macromol.2020, 161:1230-1239.
  • Kor. J. Pharmacogn.2016, 47(1):62-72
  • Phytomedicine.2018, 40:37-47
  • Phytomedicine.2023, 114:154813.
  • Magnolianin

    Catalog No: CFN96079
    CAS No: 147663-91-0
    Price: Inquiry(
    Magnolignan A

    Catalog No: CFN96188
    CAS No: 93673-81-5
    Price: $318/10mg
    Magnolignan C

    Catalog No: CFN96189
    CAS No: 93697-42-8
    Price: $318/10mg

    Catalog No: CFN95076
    CAS No: 1099687-80-5
    Price: $413/5mg
    Magnaldehyde B

    Catalog No: CFN95075
    CAS No: 92829-72-6
    Price: $318/5mg
    Magnaldehyde D

    Catalog No: CFN96172
    CAS No: 93753-33-4
    Price: Inquiry(

    Catalog No: CFN91033
    CAS No: 20601-85-8
    Price: $338/20mg

    Catalog No: CFN98872
    CAS No: 528-43-8
    Price: $30/20mg

    Catalog No: CFN99902
    CAS No: 35354-74-6
    Price: $30/20mg

    Catalog No: CFN91498
    CAS No: 68592-15-4
    Price: Inquiry(
    J Chromatogr A. 2015 May 1;1392:20-7.
    Fabrication of enzyme-immobilized halloysite nanotubes for affinity enrichment of lipase inhibitors from complex mixtures.[Pubmed: 25798866 ]
    Lipase is the key enzyme for catalyzing triglyceride hydrolysis in vivo, and lipase inhibitors have been used in the management of obesity.
    We present the first report on the use of lipase-adsorbed halloysite nanotubes as an efficient medium for the selective enrichment of lipase inhibitors from natural products. A simple and rapid approach was proposed to fabricate lipase-adsorbed nanotubes through electrostatic interaction. Results showed that more than 85% lipase was adsorbed into nanotubes in 90 min, and approximately 80% of the catalytic activity was maintained compared with free lipase. The specificity and reproducibility of the proposed approach were validated by screening a known lipase inhibitor (i.e., orlistat) from a mixture that contains active and inactive compounds. Moreover, we applied this approach with high performance liquid chromatography-mass spectrometry technique to screen lipase inhibitors from the Magnoliae cortex extract, a medicinal plant used for treating obesity. Two novel biphenyl-type natural lipase inhibitors magnotriol A and Magnaldehyde B were identified, and their IC50 values were determined as 213.03 and 96.96 μM, respectively.
    The ligand-enzyme interactions of Magnaldehyde B were further investigated by molecular docking. Our findings proved that enzyme-adsorbed nanotube could be used as a feasible and selective affinity medium for the rapid screening of enzyme inhibitors from complex mixtures.
    Phytother Res. 2013 Sep;27(9):1419-22.
    Apoptosis-inducing and antitumor activity of neolignans isolated from Magnolia officinalis in HeLa cancer cells.[Pubmed: 23192855 ]
    Two neolignans, 4'-methoxymagndialdehyde (1) and Magnaldehyde B (2), were isolated from the stem bark of Magnolia officinalis (Magnoliaceae), evaluated for apoptosis-inducing effects in human cervical epitheloid carcinoma HeLa cells.
    The apoptosis-inducing activity of compounds 1 and 2 were assessed by DNA content using flow cytometric analysis. In the immunoblotting analysis, the treatment with 1 and 2 resulted in the cleavage of procaspase-8 and -3 and poly(ADP-ribose)polymerase into active forms. In addition, in vivo, the administration of 2 to Lewis lung carcinoma-inoculated mice evidenced a significant inhibition of tumor growth (volume) with reduction of 28.7% at concentration of 20 mg/kg, as compared with the control mice.
    These findings suggest that 2 can inhibit the proliferation of tumor cells, and might be an anti-tumoric agent.
    Physalin O

    Catalog No: CFN95097
    CAS No: 120849-18-5
    Price: $413/5mg

    Catalog No: CFN95205
    CAS No: 182426-37-5
    Price: $268/10mg
    Safflospermidine B

    Catalog No: CFN95254
    CAS No: 1111082-11-1
    Price: $413/5mg
    Bidenoside C

    Catalog No: CFN95266
    CAS No: 700877-55-0
    Price: $318/5mg
    Peiioside B

    Catalog No: CFN95336
    CAS No: 1610618-91-1
    Price: $318/5mg
    Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether

    Catalog No: CFN95416
    CAS No: 74474-55-8
    Price: $318/5mg
    Epigambogellic acid

    Catalog No: CFN95438
    CAS No: 1352191-85-5
    Price: $318/5mg
    Barbaloin-related compound B

    Catalog No: CFN95455
    CAS No: 473225-22-8
    Price: $318/5mg
    Ganoderic acid GS-2

    Catalog No: CFN95549
    CAS No: 1206781-65-8
    Price: $413/5mg

    Catalog No: CFN95590
    CAS No: 92758-34-4
    Price: $318/10mg