N-Methylcorydinium iodide
N-Methylcorydinium iodide is a natural product from Glaucium oxylobum BOISS. et BUSHE.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Collect. Czech. Chem. Commun. 1985, 50, 854-860.
Quaternary alkaloids from Glaucium oxylobum BOISS. et BUSHE.[Reference:
WebLink]
METHODS AND RESULTS:
From the fraction of quaternary alkaloids of the aerial part of Glaucium oxylobum BOISS. et BUSHE (-)-trans-N-rnethylcanadinium iodide was isolated as the main alkaloid after conversion to iodides, and, in a smaller amount, (+)-N-Methylcorydinium iodide, detected for the first time in Papaveraceae, further (-)-trans-N-methylstylopinium iodide, magnoflorine iodide and a new quaternary alkaloid, N-methyldomesticinium iodide, isolated for the first time as a natural substance. In the roots, magnoflorine iodide accompanied by (+)-N-Methylcorydinium iodide represented the main component of the quaternary fraction. From both plant parts corytuberine was also isolated for the first time.
CONCLUSIONS:
In the tertiary fraction of alkaloids (+)-corydine, protopine and allocryptopine were the major components, accompanied by smaller amounts of sanguinarine, chelerythrine, chelirubine, domesticine, isoboldine and scoulerine. In the fraction of quaternary protoberberines coptisine, berberine and traces of corysamine were detected.
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