Lethedioside A
Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Nanjing University of Chinese Medicine2022, 345930.
Food Chemistry2023, 137837.
bioRxiv2021, 462065.
J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):21-39.
JPC-Journal of Planar Chromatography2023, 36:179-190
Br J Pharmacol.2018, 175(6):902-923
Asian J Beauty Cosmetol2020, 18(3): 265-272.
Biomed Pharmacother.2024, 175:116770.
Org Biomol Chem.2017, 15(31):6483-6492
Chem Res Toxicol. 2022, acs.chemrestox.2c00049.
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Journal of natural products, 1999, 62(2):241-243.
Five New Flavone 5-O-Glycosides from Lethedon tannaensis: Lethedosides and Lethediosides.[Reference:
WebLink]
METHODS AND RESULTS:
Five new 7-methoxy-flavone 5-O-glycosides were isolated from a cytotoxic MeOH extract of Lethedon tannaensis, and the structures were elucidated by 2D NMR spectral analysis and by chemical methods. Lethedoside A (1), lethedoside B (2), and lethedoside C (3) were 5-O-glucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7,3', 4'-tri-O-methytricetin, respectively; lethediosides A (4) and B (5) and a known compound 6 were 5-O-xylosylglucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7, 4'-di-O-methylapigenin, respectively.
CONCLUSIONS:
These flavonoids were either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.
