Dioscoreside C

Dioscoreside C
Product Name Dioscoreside C
CAS No.: 344912-80-7
Catalog No.: CFN95345
Molecular Formula: C52H84O22
Molecular Weight: 1061.2 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The rhizomes of Dioscorea panthaica
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $318/5mg
Dioscoreside C showed mild cytotoxicity against the cancer cell lines, A375, L929, and HeLa, in a dose-dependent manner.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Biomed Pharmacother.2021, 139:111585.
  • Nat Prod Commun.2018, 10.1177
  • Cancers (Basel).2023, 15(1):293.
  • Food Control2022, 132:108434.
  • J Cachexia Sarcopenia Muscle.2022, 13(6):3149-3162.
  • Regul Toxicol Pharmacol.2024, 149:105620.
  • Biomed Pharmacother.2023, 163:114785.
  • Front Pharmacol.2019, 10:1025
  • Phytother Res.2022, 10.1002:ptr.7626.
  • Fitoterapia.2024, 175:105955.
  • Methyl protodioscin

    Catalog No: CFN99585
    CAS No: 54522-52-0
    Price: $100/20mg
    Protodeltonin

    Catalog No: CFN93008
    CAS No: 94992-08-2
    Price: Inquiry(manager@chemfaces.com)
    Pseudoprotogracillin

    Catalog No: CFN93038
    CAS No: 637349-03-2
    Price: Inquiry(manager@chemfaces.com)
    Protogracillin

    Catalog No: CFN93054
    CAS No: 54848-30-5
    Price: Inquiry(manager@chemfaces.com)
    Methyl protogracillin

    Catalog No: CFN80084
    CAS No: 54522-53-1
    Price: $318/10mg
    Polyphyllin G

    Catalog No: CFN99955
    CAS No: 76296-75-8
    Price: Inquiry(manager@chemfaces.com)
    Parisaponin I

    Catalog No: CFN90702
    CAS No: 561007-63-4
    Price: Inquiry(manager@chemfaces.com)
    Dichotomin

    Catalog No: CFN90703
    CAS No: 53093-47-3
    Price: Inquiry(manager@chemfaces.com)
    Anemarsaponin B

    Catalog No: CFN99532
    CAS No: 139051-27-7
    Price: $318/20mg
    Anemarsaponin BIII

    Catalog No: CFN90778
    CAS No: 142759-74-8
    Price: Inquiry(manager@chemfaces.com)
    Planta Med . 2001 Dec;67(9):853-7
    Two new steroidal saponins from the rhizomes of Dioscorea panthaica and their cytotoxic activity[Pubmed: 11745024]
    Two new steroidal saponins, dioscoresides C (1) and D (2), along with a new natural product, pregnadienolone 3-O-beta-gracillimatriose (3), and two known compounds, pregnadienolone 3-O-beta-chacotrioside (4) and pseudoprotodioscin (5), were isolated from the rhizomes of Dioscorea panthaica Prain et Burkill. On the basis of extensive NMR studies and chemical evidence, dioscoresides C and D were determined to be 26-O-beta-D-glucopyranosyl-3 beta,26-dihydroxy-23(S)-methoxy-25(R)-furosta-5,20(22)-dien-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->4)]-beta-D-glucopyranoside and 26-O-beta-D-glucopyranosyl-3 beta,26-dihydroxy-20,22-seco-25(R)-furosta-5-en-20,22-dine-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1--> 4)]-beta-D-glucopyranoside. These compounds showed mild cytotoxicity against the cancer cell lines, A375, L929, and HeLa, in a dose-dependent manner.
    Yao Xue Xue Bao . 2001 Jan;36(1):42-45.
    [Isolation and identification of steroidal saponins from Dioscorea panthaica Prain et Burkill][Pubmed: 12579859]
    Aim: To investigate the chemical constituents of the rhizomes of Dioscorea panthaica Prain et Burkill and look for new active compounds. Methods: The compounds were isolated with silica gel and HPLC, and their structures were elucidated on the basis of chemical evidences and spectral analysis (IR, ESI-MS, 1HNMR, 13CNMR, DEPT, 1H-1H COSY, HMQC, HMBC, NOESY). Results: Three steroidal saponins were isolated from the rhizomes of Dioscorea panthaica. They were elucidated as 26-O-beta-D-glucopyranosyl-3 beta, 26-diol-23(S)-methoxy-25(R)-delta 5,20(22)-diene-furosta-3-O-[alpha-L-rhamnopyranosyl-(1-->2)- O-alpha-L-rhamnopyranosyl-(1-->4)]-beta-D-glucopyranoside (I), pseudoprotodioscin (II), 26-O-beta-D-glucopyranosyl-3 beta, 26-diol-25 (R)-delta 5,20(22)-diene-furosta-3-O-alpha-L-rhamnopyranosyl- (1-->2)-O-beta-D-glucopyranoside (III). Conclusion: Compound I is a new steroidal saponin and was named as Dioscoreside C. Compound II and III were obtained from this genus for the first time.
    Planta Med . 2001 Dec;67(9):853-857.
    Two new steroidal saponins from the rhizomes of Dioscorea panthaica and their cytotoxic activity[Pubmed: 11745024]
    Two new steroidal saponins, dioscoresides C (1) and D (2), along with a new natural product, pregnadienolone 3-O-beta-gracillimatriose (3), and two known compounds, pregnadienolone 3-O-beta-chacotrioside (4) and pseudoprotodioscin (5), were isolated from the rhizomes of Dioscorea panthaica Prain et Burkill. On the basis of extensive NMR studies and chemical evidence, dioscoresides C and D were determined to be 26-O-beta-D-glucopyranosyl-3 beta,26-dihydroxy-23(S)-methoxy-25(R)-furosta-5,20(22)-dien-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->4)]-beta-D-glucopyranoside and 26-O-beta-D-glucopyranosyl-3 beta,26-dihydroxy-20,22-seco-25(R)-furosta-5-en-20,22-dine-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1--> 4)]-beta-D-glucopyranoside. These compounds showed mild cytotoxicity against the cancer cell lines, A375, L929, and HeLa, in a dose-dependent manner.
    2''-O-Galloylquercitrin

    Catalog No: CFN95041
    CAS No: 80229-08-9
    Price: $418/5mg
    7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin

    Catalog No: CFN95070
    CAS No: 1092952-62-9
    Price: Inquiry(manager@chemfaces.com)
    6''-O-Acetylsaikosaponin D

    Catalog No: CFN95090
    CAS No: 64340-45-0
    Price: $288/5mg
    3,7,25-Trihydroxycucurbita-5,23-dien-19-al

    Catalog No: CFN95150
    CAS No: 85372-65-2
    Price: $318/5mg
    Pueroside A

    Catalog No: CFN95177
    CAS No: 100692-52-2
    Price: $318/5mg
    Astin C

    Catalog No: CFN95189
    CAS No: 148057-23-2
    Price: $318/10mg
    N-trans-caffeoyltyramine

    Catalog No: CFN95265
    CAS No: 103188-48-3
    Price: $388/20mg
    9-Octadecenedioic acid

    Catalog No: CFN95301
    CAS No: 4494-16-0
    Price: $100/20mg
    Foliachinenoside C

    Catalog No: CFN95361
    CAS No: 1041180-87-3
    Price: $368/5mg
    Taxezopidine H

    Catalog No: CFN95562
    CAS No: 205440-23-9
    Price: $318/5mg