Echitoveniline
Echitoveniline is a natural product from Alstonia venenata R.Br.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Kaohsiung J Med Sci.2023, 10.1002/kjm2.12764
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Sci Rep.2019, 9:12132
JPC-Journal of Planar Chromatography 2017, 30(4)
International J of Green Pharmacy2019, 13(3)
J of Pharmaceutical Analysis2020, doi: 10.1016
Brain Res Bull.2024, 218:111103.
Toxicol Appl Pharmacol.2021, 427:115668.
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Tetrahedron, 1979, 35(9):1151-1157.
Alkaloids of Alstonia venenata R.Br.[Reference:
WebLink]
METHODS AND RESULTS:
Structures and absolute stereochemistry of (-)-Echitoveniline, (-)-11-methoxyEchitoveniline and (-)-11-methoxyechitovenedine, three new indole alkaloids of the vincadifformine type, isolated from the fruits and leaves of Alstonia venenata R.Br., have been established as 3b, 3c and 3d, respectively, on the basis of spectral and chemical evidence.
CONCLUSIONS:
A plausible mechanism of the LAH reduction of the δ-lactones8b and8c to the corresponding diols 9b and 9c has been discussed.
