11-Hydroxytabersonine

11-Hydroxytabersonine
Product Name 11-Hydroxytabersonine
CAS No.: 22149-28-6
Catalog No.: CFN98205
Molecular Formula: C21H24N2O3
Molecular Weight: 352.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The peels of Melodinus fusiformis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
11-Hydroxytabersonine has antitumor activety.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Chinese Traditional & Herbal Drugs,1998,29(12):793-5.
    Studies on the Chemical Constituents of Hemsley Melodinus (Melodinus hemsleyanus)[Reference: WebLink]

    METHODS AND RESULTS:
    10 compounds were isolated from Melodinus hemsleyanus Diels. and their structures were determined by spectral analysis and chemical reactions. They were 11-Hydroxytabersonine (Ⅰ), scandine (Ⅱ), 10-hydroxyscandine(Ⅲ), tubotaiwine(Ⅳ), tubotaiwine N-oxide(Ⅴ), 15α-hydroxykopsinine(Ⅵ),vincoline(Ⅶ), 19R-vindolinine N-oxide(Ⅷ), 16 β-hydroxy-19R-vindolinine (Ⅸ) and a new compound, 16β-hydroxy-19S-vindoline N-oxide(Ⅹ).
    CONCLUSIONS:
    Pharmacological screening revealed that Ⅰ had antitumor activety.
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    Chemical constituents from twigs and leaves of Melodinus hemsleyanus.[Pubmed: 23947135]
    To study the chemical constituents in the twigs and leaves of Melodinus hemsleyanus.
    METHODS AND RESULTS:
    The chemical constituents were isolated by silica gel, ODS and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. Fourteen compounds were isolated from the 95% ethanol extract of the twigs and leaves of M. hemsleyanus. Their structures were identified as 11-Hydroxytabersonine (1), venalstonid (2), sandine (3), oleanolic acid (4), ursolic acid (5), betulin (6), (+)-pinoresinol (7), (-)-syringaresinol (8), 8-hydroxypinoresinol (9), (-)-latifolin (10), cirsilineol (11), loganin (12), dibutylterephthalate (13), and beta-sitosterol (14).
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    CONCLUSIONS:
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