4,2'-Dihydroxy-4'-methoxychalcone
4,2'-Dihydroxy-4'-methoxychalcone shows allergy-preventive effects.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Food Chem.2023, 424:136383.
PLoS One.2022, 17(4):e0267007.
Pharmacia2022, 69(3): 883-890.
Microchemical Journal2023, 194:109249
Universiti Tunku Aboul Rahman2023, 6263.
Sci Rep.2023, 13(1):14594.
The Japan Society for Analytical Chemistry2018, 67(4):201-206
Exp Parasitol.2018, 194:67-78
Biomed Pharmacother.2022, 156:113929.
J Agric Food Chem.2024, acs.jafc.4c01387.
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Chem Pharm Bull (Tokyo). 2007 Apr;55(4):675-8.
Allergy-preventive flavonoids from Xanthorrhoea hastilis.[Pubmed:
17409571]
Allergy-preventive activity was demonstrated for an extract of resins from Xanthorrhoea hastilis R. BR. in a search for allergy-preventive substances from natural sources.
METHODS AND RESULTS:
By bioassay-directed fractionation of this plant extract, a new flavanone, 3',5'-dihydroxy-7,4'-dimethoxyflavanone (1), and two new chalcones, 3,5,2'-trihydroxy-4,4'-dimethoxychalcone (2) and 5,2'-dihydroxy-3,4,4'-trimethoxychalcone (3), were isolated together with five known compounds, 5'-hydroxy-7,3',4'-trimethoxyflavanone (4), 3'-hydroxy-7,4'-dimethoxyflavanone (5), liquiritigenin 7-methyl ether (6), 4,2'-Dihydroxy-4'-methoxychalcone (7) and sakuranetin (8).
CONCLUSIONS:
The structures of 1, 2 and 3 were elucidated by spectroscopic methods. All of these compounds showed allergy-preventive effects.
