Momordicoside X
Momordicoside X displays moderate insulin secretion activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Cosmet Dermatol.2022, 21(1):396-402.
J Appl Toxicol.2024, jat.4615.
ACS Omega.2024, 9(12):14356-14367.
Front Cell Dev Biol.2021, 9:638174.
Applied Biological Chemistry2023, 66:42.
BMC Complement Altern Med.2018, 18(1):221
Nutrients.2019, 11(11):E2694
Int J Mol Sci.2021, 22(19):10405.
Sci Rep.2024, 14(1):3684.
Indian Journal of Science and Technology2023, 16(SP1):48-56.
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Planta Med. 2010 Oct;76(15):1758-61.
Cucurbitane-type triterpenoids from Momordica charantia.[Pubmed:
20379957 ]
METHODS AND RESULTS:
One new cucurbitane-type triterpenoid glycoside, Momordicoside X ( momordicoside U, 1), together with five known cucurbitane-type triterpenoids and related glycosides, 3 β,7 β,25-trihydroxycucurbita-5,23( E)-dien-19-al ( 2), momordicine I ( 3), momordicine II ( 4), 3-hydroxycucurbita-5,24-dien-19-al-7,23-di- O- β-glucopyranoside ( 5), and kuguaglycoside G ( 6), were isolated from the whole plant of MOMORDICA CHARANTIA. Their structures were determined by chemical and spectroscopic methods.
CONCLUSIONS:
Momordicoside X ( 1) was evaluated for insulin secretion activity in an IN VITRO insulin secretion assay and displayed moderate activity.
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