Methyllinderone
Catalog No: CFN98631
Methyllinderone is a human chymase inhibitor, it has antioxidant property, it also shows moderate to weak antifungal activities against various pathogenic fungi. Methyllinderone can inhibit farnesyl protein transferase with IC50 value of 55.3+/-4.1microM and selectively inhibit the growth of H-ras-transformed rat-2 cell lines with a GI50 value of 0.3 microM. Methyllinderone shows significant cytotoxicity against mouse melanoma (B16-F10), human acetabulum fibrosarcoma (HT1080), and choronic myelogenous leukemia (K562) cancer cell lines with ED(50) values of 2.2, 2.5, 8.3 mug/ml, respectively.