Hot Products

Myrislignan
Catalog No: CFN99752

Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induced apoptosis and cell cycle arrest in A549 cells.

Myristic acid
Catalog No: CFN93243

Dietary myristic acid modifies the HDL-cholesterol concentration and liver scavenger receptor BI expression in the hamster. Myristic acid increases the activity of dihydroceramide Δ4-desaturase 1 through its N-terminal myristoylation, it also supports the immediate inhibitory effect of lauric acid on ruminal methanogens and methane release.

Myristicin
Catalog No: CFN90589

Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements. Myristicin can induce apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, caspase-3 activation, PARP-cleavage and DNA fragmentation.

Myrrhone
Catalog No: CFN91042

Reference standards.

N-(3-Methoxybenzyl)oleamide
Catalog No: CFN90847

Macamides (N-(3-methoxybenzyl)oleamide (MAC 18:1), N-(3-methoxybenzyl)linoleamide (MAC 18:2) and N-(3-methoxybenzyl)linolenamide (MAC 18:3) )achieve their neuroprotective effects by binding to CB1 receptors to protect against Mn-induced toxicity in U-87 MG glioblastoma cells. Additionally these macamides, in a manner similar to the analogous endocannabinoid AEA, interact with other targets such as PPARγ to regulate metabolism and energy homeostasis, cell differentiation and inflammation.

N-(3-Methoxybenzyl)palmitamide
Catalog No: CFN90846

N-(3-methoxybenzyl)palmitamide is a promising inhibitor of fatty acid amide hydrolase (FAAH) and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders. N-(3-Methoxybenzyl)palmitamide can counteract the toxicity produced by Aβ (25-35).

N-(p-Coumaroyl) serotonin
Catalog No: CFN91127

N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving vascular distensibility and in reducing cardiovascular risk.N-(p-Coumaroyl) serotonin has a suppressive effect on proinflammatory cytokine production from monocytes, and this effect is based in part on the suppression of cytokine mRNA expression through inhibition of NF-kappaB activation.

N1,N10-Bis(p-coumaroyl)spermidine
Catalog No: CFN99248

Reference standards.

N1,N5,N10-(E)-tri-p-coumaroylspermidine
Catalog No: CFN95256

N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.

N1,N5,N10-(Z)-tri-p-coumaroylspermidine
Catalog No: CFN95253

N1,N5,N10-(Z)-tri-p-coumaroylspermidine shows weak inhibition effect on [3H]-5-HT reuptake in rat brain synaptosomes.