Iristectorin A

Iristectorin A
Product Name Iristectorin A
CAS No.: 37744-61-9
Catalog No.: CFN95037
Molecular Formula: C23H24O12
Molecular Weight: 492.4 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Iris tectorum
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $333/5mg
Iristectorin A is a natural product from Iris tectorum.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int J Mol Sci. 2014, 15(5):8443-57
  • BMC Complement Altern Med.2017, 17(1):393
  • BMC Complement Altern Med.2014, 14:242
  • Nat Commun.2019, 10(1):2745
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • Plos One.2019, 15(2):e0220084
  • Org Biomol Chem.2017, 15(31):6483-6492
  • The Korea Journal of Herbology2016, 29-35
  • Front Plant Sci.2018, 9:1424
  • Molecules.2019, 24(2):329
  • Sissotrin

    Catalog No: CFN97005
    CAS No: 5928-26-7
    Price: $268/5mg
    Genistein 7,4'-di-O-beta-D-glucopyranoside

    Catalog No: CFN90953
    CAS No: 36190-98-4
    Price: $268/20mg
    6''-O-Malonylgenistin

    Catalog No: CFN90631
    CAS No: 51011-05-3
    Price: $518/10mg
    Glycitin

    Catalog No: CFN99105
    CAS No: 40246-10-4
    Price: $70/20mg
    6''-O-Acetylglycitin

    Catalog No: CFN93455
    CAS No: 134859-96-4
    Price: Inquiry(manager@chemfaces.com)
    6''-O-xylosyl-glycitin

    Catalog No: CFN80151
    CAS No: 231288-18-9
    Price: Inquiry(manager@chemfaces.com)
    Odoratin-7-O-beta-D-glucopyranoside

    Catalog No: CFN91882
    CAS No: 210413-47-1
    Price: Inquiry(manager@chemfaces.com)
    Tectoridin

    Catalog No: CFN99921
    CAS No: 611-40-5
    Price: $68/20mg
    Tectorigenin 7-O-xylosylglucoside

    Catalog No: CFN90784
    CAS No: 231288-19-0
    Price: $268/5mg
    Kakkalide

    Catalog No: CFN95052
    CAS No: 58274-56-9
    Price: $260/10mg
    J Nat Prod. 2005 Mar;68(3):361-4.
    Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.[Pubmed: 15787436 ]

    METHODS AND RESULTS:
    From the rhizomes of Belamcanda chinensis, three new compounds, belalloside A (1), belalloside B (2), and belamphenone (3), along with 13 known compounds, resveratrol (4), iriflophenone (5), irisflorentin (6), tectorigenin (7), irilin D (8), tectoridin (9), Iristectorin A (10), iristectorin B (11), hispiduloside, androsin, irigenin, iridin, and jaceoside, have been isolated and characterized.
    CONCLUSIONS:
    Isolates were evaluated for their cell proliferation stimulatory activity against the MCF-7 and T-47D human breast cancer cell lines. Along with 4, 5, 7, and 9, 3 was shown to stimulate not only MCF-7 but also T-47D human breast cancer cell proliferation.
    J Sep Sci. 2016 Dec;39(23):4533-4543.
    Ultrafiltration-LC-MS combined with semi-preparative HPLC for the simultaneous screening and isolation of lactate dehydrogenase inhibitors from Belamcanda chinensis.[Pubmed: 27734585]
    Stroke represents the fourth leading cause of death in the USA and the second leading cause of death worldwide. Lactate dehydrogenase inhibitors are widely used in the treatment of ischemic stroke and natural products are considered a promising source of novel lactate dehydrogenase inhibitors.
    METHODS AND RESULTS:
    In this study, we used PC12 cells to determine the protective effect of extracts from the herb Belamcanda chinensis following toxic challenge. Using ultrafiltration high-performance liquid chromatography coupled with photo-diode array detection and electrospray ionization mass spectrometry, we screened and identified isoflavonoids from Belamcanda chinensis extracts. Semi-preparative high-performance liquid chromatography was then applied to separate and isolate the active constituents. Using these methods, we identified six major compounds in Belamcanda chinensis as lactate dehydrogenase inhibitors: tectoridin, Iristectorin A, iridin, tectorigenin, irigenin, and irisflorentin, which were then isolated to >92% purity. This is the first report that Belamcanda chinensis extracts contain potent lactate dehydrogenase inhibitors.
    CONCLUSIONS:
    Our results demonstrate that the systematic isolation of bioactive components from Belamcanda chinensis guided by ultrafiltration high-performance liquid chromatography coupled with photo-diode array detection and electrospray ionization mass spectrometry represents a feasible and efficient technique that could be extended for the identification and isolation of other enzyme inhibitors.
    6',7'-Dihydroxybergamottin

    Catalog No: CFN98307
    CAS No: 264234-05-1
    Price: $438/10mg
    Vicenin -3

    Catalog No: CFN92032
    CAS No: 59914-91-9
    Price: $198/20mg
    Batatasin III

    Catalog No: CFN92689
    CAS No: 56684-87-8
    Price: $368/5mg
    Arnicolide C

    Catalog No: CFN91996
    CAS No: 34532-67-7
    Price: $398/5 mg
    Bisabolangelone

    Catalog No: CFN91876
    CAS No: 30557-81-4
    Price: $433/10mg
    Monomethyl lithospermate

    Catalog No: CFN91005
    CAS No: 933054-33-2
    Price: $333/10mg
    Polygalasaponin XLIX

    Catalog No: CFN95117
    CAS No: 1033593-12-2
    Price: $318/10mg
    7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one

    Catalog No: CFN95140
    CAS No: 100667-52-5
    Price: $318/5mg
    3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin

    Catalog No: CFN95154
    CAS No: 148210-00-8
    Price: $413/5mg
    Ginsenoside MC

    Catalog No: CFN95232
    CAS No: 175484-06-7
    Price: $318/10mg