Norscopolamine

Norscopolamine
Product Name Norscopolamine
CAS No.: 4684-28-0
Catalog No.: CFN96076
Molecular Formula: C16H19NO4
Molecular Weight: 289.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Atropanthe sinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $513/5mg
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Vietnam Journal of Food Control2022, 5(3):pp.390-401.
  • J Separation Science & Technology2016, 51:1579-1588
  • Int J Mol Sci.2019, 21(1):E265
  • J Ethnopharmacol.2020, 249:112396
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  • Norscopolamine

    Catalog No: CFN96076
    CAS No: 4684-28-0
    Price: $513/5mg
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    Green Chemistry, 2012, 14(4):1189-1195.
    One-pot oxidative N-demethylation of tropane alkaloids with hydrogen peroxide and a FeIII-TAML catalyst.[Reference: WebLink]

    METHODS AND RESULTS:
    The oxidative N-demethylation of tropane alkaloids to their nortropane derivatives has been investigated using H2O2 and an iron(III) tetraamido macrocycle (FeIII-TAML) catalyst. The yields of the nortropanes were found to be dependent on the amount of H2O2 used in the reaction, the catalyst loading, the nature of the organic co-solvent and the type of tropine substrate. N-Hydroxy-nortropane, N-formyl-nortropane and tropane-N-oxide derivatives were identified as by-products of the reaction.
    CONCLUSIONS:
    After screening various reaction conditions, the optimised conditions were applied to the N-demethylation of atropine and scopolamine at preparative scales and the desired products, noratropine and Norscopolamine, obtained following one pot reactions in good yields and high purity without the need for any chromatographic purification steps.
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