Pilosidine

Pilosidine
Product Name Pilosidine
CAS No.: 229971-57-7
Catalog No.: CFN95110
Molecular Formula: C23H26O11
Molecular Weight: 478.5 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Curculigo capitulata
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $413/5mg
Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Pharmaceut Biomed2020, 178:112894
  • J Ethnopharmacol.2019, 244:112074
  • Acta horticulturae2017, 1158:257-268
  • Phytother Res.2019, 33(3):676-689
  • Int J Oncol.2019, 55(1):320-330
  • Phys Chem Chem Phys.2018, 20(23):15986-15994
  • Journal of Life Science2018, 917-922
  • Comput Biol Chem.2019, 83:107096
  • BMC Complement Altern Med.2014, 14:242
  • Front Pharmacol.2016, 7:460
  • Pilosidine

    Catalog No: CFN95110
    CAS No: 229971-57-7
    Price: $413/5mg
    Octahydrocurcumin

    Catalog No: CFN90584
    CAS No: 36062-07-4
    Price: $388/20mg
    Hexahydrocurcumin

    Catalog No: CFN97749
    CAS No: 36062-05-2
    Price: Inquiry(manager@chemfaces.com)
    Tetrahydrocurcumin

    Catalog No: CFN90583
    CAS No: 36062-04-1
    Price: $188/20mg
    Demethoxycurcumin

    Catalog No: CFN99185
    CAS No: 22608-11-3
    Price: $100/20mg
    Bisdemethoxycurcumin

    Catalog No: CFN99186
    CAS No: 33171-05-0
    Price: $80/20mg
    Curcumin

    Catalog No: CFN98686
    CAS No: 458-37-7
    Price: $30/20mg
    Dimethylcurcumin

    Catalog No: CFN90607
    CAS No: 52328-98-0
    Price: $218/20mg
    Tetramethylcurcumin

    Catalog No: CFN90605
    CAS No: 52328-97-9
    Price: Inquiry(manager@chemfaces.com)
    Dihydrocurcumin

    Catalog No: CFN99540
    CAS No: 76474-56-1
    Price: $288/20mg
    Phytochemistry, 2000, 55(5):411-417.
    Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity[Pubmed: 11140602 ]

    METHODS AND RESULTS:
    From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, Pilosidine, previously obtained only as the tetra-O-methyl derivative, were isolated.
    CONCLUSIONS:
    Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
    Farmaco. 2001 May-Jul;56(5-7):353-6.
    Studies on vasoconstrictor activity of Curculigo pilosa extracts and of its isolated compounds.[Pubmed: 11482757]

    METHODS AND RESULTS:
    The Curculigo pilosa total extract, its butanolic fraction (0.5 microg-100 mg/kg) and the most active in vitro compound structurally similar to adrenaline, Pilosidine (10 ng-l mg/kg), caused a reversible and dose-dependent increase in blood pressure in anaesthetized rat. This hypertensive effect is partially reversed (90%) by the prior administration of phentolamine (1 mg/kg) and abolished by pre-treatment with phentolamine (1 mg/kg) and atenolol (100 microg/kg). Neither tachiphylaxis nor any toxic effects were observed.
    CONCLUSIONS:
    These experimental findings suggest an interaction between C. pilosa and the peripheral adrenergic system (particularly with alpha1 and beta1 receptors); the structure of the bioactive glucosides could be important in evoking this effect.
    Chebulinic acid

    Catalog No: CFN92296
    CAS No: 18942-26-2
    Price: $218/10mg
    3-Epidehydropachymic acid

    Catalog No: CFN92738
    CAS No: 168293-15-0
    Price: $338/5mg
    20(21)-Dehydrolucidenic acid A

    Catalog No: CFN90829
    CAS No: 852936-69-7
    Price: $358/5mg
    Secologanic acid

    Catalog No: CFN95028
    CAS No: 60077-46-5
    Price: $318/10mg
    Ginsenoside F5

    Catalog No: CFN95034
    CAS No: 189513-26-6
    Price: $298/20mg
    Maculosidin

    Catalog No: CFN95126
    CAS No: 522-19-0
    Price: $413/5mg
    Leachianol G

    Catalog No: CFN95146
    CAS No: 164204-62-0
    Price: $368/5mg
    (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol

    Catalog No: CFN95195
    CAS No: 87095-75-8
    Price: $318/5mg
    Epischisandrone

    Catalog No: CFN95212
    CAS No: 98619-26-2
    Price: $413/5mg
    Isovalerylshikonin

    Catalog No: CFN95222
    CAS No: 52387-14-1
    Price: $318/10mg