3alpha,6beta-Ditigloyloxytropan-7beta-ol
3alpha,6beta-Ditigloyloxytropan-7beta-ol is a natural product from Datura metel.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
Dicle Tip Dergisi2020, 47(2),423-430.
J Cell Biochem.2022, 123(7):1222-1236.
Journal of Food Hygiene and Safety2019, 34(5):413-420
Foods.2024, 13(19):3092.
Kangwon National University2022, 37(1):29-37
Evid Based Complement Alternat Med.2018, 2018:4259603
Mol Plant Pathol.2023, 24(2):123-141.
Int. J. Mol. Sci.2023, 24(20),15294.
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Phytochemistry, 1973 , 12 (9) :2197-2201.
Biosynthesis of the tigloyl esters in Datura: The role of 2-methylbutyric acid.[Reference:
WebLink]
METHODS AND RESULTS:
Datura innoxia plants were wick fed with (±)-2-methylbutyric acid-[1-14C] and harvested after 7 days. The root alkaloids 3α,6β-ditigloyloxytropane and 3alpha,6beta-Ditigloyloxytropan-7beta-ol were isolated and degraded.
CONCLUSIONS:
In each case the radioactivity was located in the ester carbonyl group indicating that this acid is an intermediate in the biosynthesis of tiglic acid from l-isoleucine. On the other hand, (±)-2-hydroxy-2-methylbutyric acid-[1-14C], which was fed to hydroponic cultures of Datura innoxia alongside isoleucine[U-14C] positive control plants, is not an intermediate.
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