Isomartynoside

Isomartynoside
Product Name Isomartynoside
CAS No.: 94410-22-7
Catalog No.: CFN97525
Molecular Formula: C31H40O15
Molecular Weight: 652.7 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The roots of Rehmannia glutinosa
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $413/5mg
Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Sci Rep.2019, 9:19059
  • J Chromatogr Sci.2015, 53(5):824-9
  • Bioorg Med Chem.2020, 28(12):115553.
  • Advances in Traditional Medicine 2021, 21:779-789.
  • Front Plant Sci.2024, 15:1458916.
  • Korean Journal of Pharmacognosy2017, 48(4):320-328
  • Food Chem.2017, 228:301-314
  • Pharmaceuticals (Basel).2024, 17(4):442.
  • Nutrients.2023, 15(12):2644.
  • Br J Pharmacol.2020, 10.1111
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