Methyl ganoderate B
Methyl Ganoderic acid B, a triterpenoid isolated from Ganoderma lucidum, exhibits neuronal survival-promoting effects similar to nerve growth factor (NGF-like).
Methyl Ganoderic Acid B exhibits protective effects on fibroblasts expressing TrkA or TrkB receptors, with ED50 values of 0.69 ± 0.22 and 0.68 ± 0.21 μg/mL, respectively.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Zhong Yao Cai . 2008 Jan;31(1):41-44.
[Chemical constituents of the spores of Ganoderma lucidum][Pubmed:
18589746]
Objective: To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum.
Methods: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data.
Results: From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), Methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively.
Conclusion: Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.
Zhongguo Zhong Yao Za Zhi . 2016 Mar;41(6):1075-1080.
[Triterpenoids from Ganoderma theaecolum][Pubmed:
28875673]
Fifteenlanostane triterpenoids were isolated from the ethanol extract of Ganoderma theaecolum by means of preparative HPLC,column chromatography over silica gel,ODS and were identified as lucidone C(1),lucidone D(2),7-oxo-ganoderic acid Z2(3),7-oxo-ganoderic acid Z(4),ganoderenicacid H(5),ganoderenic acid B(6),3β,7β-dihydroyl-11,15,23-trioxo-lanost-8,16-dien-26-oic acid(7),3β,7β-dihydroyl-11,15,23-trioxo-lanost-8,16-dien-26-oic acid methyl ester(8),ganolucidic acid B(9),ganolucidate F(10),methyl ganoderate C2(11),ganoderic acid ζ(12),ganoderic acid AP3(13),Methyl ganoderate B(14),and ganoderol B(15). Compounds 1-15 were isolated from this specie for the first time.
