Ganoderic acid LM2
Ganoderic acid LM2 exhibits potent enhancement of ConA-induced mice splenocytes proliferation in vitro.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Int J Mol Sci.2019, 20(16):E4015
Phytochemistry Letters2021, 43:80-87.
Evid Based Complement Alternat Med.2018, 2018:3610494
Phytomedicine.2023, 114:154813.
Biorxiv2019, 10.1101
Evid Based Complement Alternat Med.2021, 2021:6687513.
Molecular & Cellular Toxicology2017, 13(3):271-278
Free Radic Biol Med.2016, 97:307-319
Anim Cells Syst (Seoul).2024, 28(1):381-391.
Cell Death Dis.2019, 10(12):882
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J Asian Nat Prod Res. 2002 Jun;4(2):129-34.
A new lanostane-type triterpene from the fruiting bodies of Ganoderma lucidum.[Pubmed:
12067158]
A new lanostane-type triterpene, named Ganoderic acid LM2 (5), was isolated from the fruiting bodies of Ganoderma lucidum.
METHODS AND RESULTS:
Its structure was characterized as (23S) 7beta, -dihydroxy-3, 11, 15-trioxo-5alpha-lanosta-8, 24-dien-26-oic acid by 1D- and 2D-NMR spectra. In addition, a known triterpene, ganoderic acid epsilon (4), was obtained. Both of them exhibited potent enhancement of ConA-induced mice splenocytes proliferation in vitro.
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