Aristolactam AII

Aristolactam AII
Product Name Aristolactam AII
CAS No.: 53948-07-5
Catalog No.: CFN96013
Molecular Formula: C16H11NO3
Molecular Weight: 265.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Yellow powder
Targets: PAFR
Source: The herbs of Aristolochia debilis Sieb. et Zucc
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Biomed Pharmacother.2024, 176:116765.
  • Int J Mol Sci.2022, 23(21):13406.
  • Fitoterapia.2024, 177:106138.
  • J Nat Med.2020, 74(3):550-560.
  • Food Sci Biotechnol.2023, 32(9):1215-1223.
  • Phytomedicine.2019, 55:229-237
  • Front Pharmacol.2021, 12:635510.
  • Korean Journal of Plant Resources2021, 34(1):52-58.
  • Analytical methods2019, 11(6)
  • Arch Toxicol.2024, 98(5):1415-1436.
  • Griffithinam

    Catalog No: CFN97866
    CAS No: 240122-32-1
    Price: Inquiry(manager@chemfaces.com)
    Aristololactam II

    Catalog No: CFN91875
    CAS No: 55610-00-9
    Price: Inquiry(manager@chemfaces.com)
    Aristololactam I

    Catalog No: CFN90312
    CAS No: 13395-02-3
    Price: $338/20mg
    7-(2'-Deoxyadenosin-N6-yl)aristolactam I

    Catalog No: CFN90417
    CAS No: 127191-86-0
    Price: Inquiry(manager@chemfaces.com)
    Aristolactam AIIIa

    Catalog No: CFN97551
    CAS No: 97399-91-2
    Price: Inquiry(manager@chemfaces.com)
    Aristolactam BII

    Catalog No: CFN98903
    CAS No: 53948-09-7
    Price: Inquiry(manager@chemfaces.com)
    Aristolactam BIII

    Catalog No: CFN98904
    CAS No: 53948-10-0
    Price: Inquiry(manager@chemfaces.com)
    Piperolactam C

    Catalog No: CFN97948
    CAS No: 116064-76-7
    Price: Inquiry(manager@chemfaces.com)
    Aristolactam FI

    Catalog No: CFN99222
    CAS No: 112501-42-5
    Price: Inquiry(manager@chemfaces.com)
    Aristolactam AII

    Catalog No: CFN96013
    CAS No: 53948-07-5
    Price: Inquiry(manager@chemfaces.com)
    Phytochemistry. 2013 Feb;86:121-6.
    Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis.[Pubmed: 23158725]

    METHODS AND RESULTS:
    Chemical investigation of the CH(2)Cl(2)/CH(3)OH extracts from aerial parts of the Australian plant Goniothalamus australis has resulted in the isolation of two pyridocoumarin alkaloids, goniothalines A (1) and B (2) as well as eight known natural products, Aristolactam AII (3), enterocarpam II (4), caldensine (5), sauristolactam (6), (-)-anonaine (7), asimilobine (8), altholactone (9) and ( )-goniofufurone (10). The chemical structures of all compounds were determined by extensive spectroscopic and spectrometric analysis. Methylation of 2 using TMS-diazomethane afforded 1, which unequivocally established that both 1 and 2 possessed a 10-methyl-2H-pyrano[2,3-f]quinolin-2-one skeleton. These pyridocoumarin alkaloids are putatively proposed to arise biosynthetically from an aporphinoid precursor. Compounds 1-10 were evaluated for in vitro antimalarial activity against a chloroquine-sensitive Plasmodium falciparum line (3D7).
    CONCLUSIONS:
    Sauristolactam (6) and (-)-anonaine (7) exhibited the most potent antiparasitic activity with IC(50) values of 9 and 7 μM, respectively.
    Caraganaphenol A

    Catalog No: CFN95093
    CAS No: 174916-31-5
    Price: $333/5mg
    6'-Feruloylnodakenin

    Catalog No: CFN95202
    CAS No: 131623-14-8
    Price: $318/10mg
    Peucenidin

    Catalog No: CFN95272
    CAS No: 33044-93-8
    Price: $318/5mg
    Euphorbia factor L25

    Catalog No: CFN95339
    CAS No: 303174-98-3
    Price: $368/5mg
    3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside

    Catalog No: CFN95375
    CAS No: 352280-34-3
    Price: $413/5mg
    Theaflavanoside II

    Catalog No: CFN95380
    CAS No: 943785-09-9
    Price: $318/5mg
    Rhamnocitrin 3-galactoside

    Catalog No: CFN95474
    CAS No: 99878-05-4
    Price: $318/10mg
    Symplocoside

    Catalog No: CFN95552
    CAS No: 76502-76-6
    Price: $318/5mg
    Mahuannin B

    Catalog No: CFN95554
    CAS No: 82796-37-0
    Price: $318/5mg
    Iristectorin A-6''-O-glucoside

    Catalog No: CFN95597
    CAS No: 86849-71-0
    Price: $413/5mg