5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside | CAS:942626-74-6

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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J Ethnopharmacol.2021, 267:113615.

LWT2024, 200:116184.

Tropical J. of Pha. Research2017, 16(3):543-552

Sci Rep.2017, 7:467-479

Int J Mol Sci.2017, 18(5)

J Appl Biol Chem2021, 64(3):245-251.

Antioxidants (Basel).2022, 11(10):1929.

J Appl Toxicol.2024, jat.4615.

J Exp Bot.2016, 67(12):3777-88

VNU J Sci: Med. Pharm. Sci.2024, 40(2):21-30.

Chem Pharm Bull (Tokyo). 2007 Mar;55(3):455-8.

Secondary metabolites from Andrographis paniculata.[Pubmed: 17329890 ]

METHODS AND RESULTS:
Two new flavonoid glycosides, 5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside (1) and 5-hydroxy-7,8,2',5'-tetramethoxy-flavone-5-O-beta-D-glucopyranoside (2), and a new diterpenoid, andrographic acid (3), along with andrographidine A (4) were isolated from Andrographis paniculata, and their structures were determined on the basis of physicochemical and spectroscopic analysis. Compound 3 was evaluated for cytotoxicity to KB cells along with andrographolide, isoandrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide obtained from A. paniculata in the present study.
CONCLUSIONS:
Cytotoxicity was observed for andrographolide and isoandrographolide with ED50 values of 6.5 and 5.1 microg/ml, respectively.

Product Name	5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside
CAS No.:	942626-74-6
Catalog No.:	CFN95209
Molecular Formula:	C₂₃H₂₆O₁₀
Molecular Weight:	462.5 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Andrographis paniculata
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price:	$318/10mg