Alboctalol

Alboctalol
Product Name Alboctalol
CAS No.: 62394-00-7
Catalog No.: CFN97075
Molecular Formula: C28H24O8
Molecular Weight: 488.5 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Cudrania tricuspidata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Alboctalol inhibits mushroom tyrosinase activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Hanoi University of Pharmacy2023, 14(1):30-39.
  • Chin. Med.J.Res. Prac.2017, 31(4)
  • Int J Mol Sci.2024, 25(5):2914.
  • Journal of Food Composition and Analysis2021, 100:103905.
  • J Ethnopharmacol.2024, 326:117902.
  • Int J Mol Sci.2022, 23(23):14826.
  • J Nat Med.2021, doi: 10.1007.
  • J.Pharm. & Biome. Anal.2023, 2: 100018.
  • J Drug Target.2016, 24:1-28
  • FARMACIA2023, Vol.71,3.
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    METHODS AND RESULTS:
    Twenty-four compounds, including the previously unknown artoxanthocarpuone A, artoxanthocarpuone B, hydroxylakoochin A, methoxylakoochin A, epoxylakoochin A, and artoxanthol, were isolated and characterized spectroscopically. Among them, artoxanthol is stilbene oligomer presumably constructed in a 5,11,12-triphenyl hexahydrochrysene scaffold by a Diels-Alder type of reaction, for which a biosynthetic pathway is proposed. Artoxanthol, Alboctalol, steppogenin, norartocarpetin, resveratrol, oxyresveratrol, and chlorophorin potently inhibited mushroom tyrosinase activity with IC50 values from 0.9 to 5.7μM that were all far stronger than the positive controls. Artoxanthocarpuone A, artoxanthocarpuone B, methoxylakoochin A, lakoochin A, cudraflavone C, artonin A, resveratrol, and chlorophorin reduced tyrosinase activity and inhibited α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells without affecting cell proliferation.
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