Shegansu B
Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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mBio.2020, 11(3):e00686-20.
J. Food Composition and Anal.2022, V 109:104482.
Cell Death Dis.2019, 10(12):882
Separations2023, 10(11), 567;
J Nat Prod.2018, 81(4):966-975
Sci Rep.2017, 7(1):3249
Applied Physics B2021, 127(92).
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Planta Med. 2010 Nov;76(16):1874-6.
In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.[Pubmed:
20539973]
METHODS AND RESULTS:
The anti-influenza viral activities of six stilbenoids from the lianas of Gnetum pendulum C. Y. Cheng were evaluated with two different assays, neuraminidase (NA) activity assay and cytopathic effect (CPE) reduction assay.
CONCLUSIONS:
The NA assay results showed that all six stilbenoids exerted an NA inhibitory effect, while the CPE assay indicated that among them, isorhapontigenin (2), gnetupendin B (3), Shegansu B (4), and gnetin D 6) exhibit significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 µg/mL in comparison to the positive controls oseltamivir acid and ribavirin whose IC(50) values were 0.040 and 5.54 µg/mL, respectively.
J Asian Nat Prod Res. 2000;2(3):169-75.
A new stilbene dimer--shegansu B from Belamcanda chinensis.[Pubmed:
11256690]
METHODS AND RESULTS:
A new dimeric stilbene, named Shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectroscopic evidence including 2D-NMR studies.
