Corymboside

J Pharm Pharmacol . 2000 Mar;52(3):347-52.

Chemical characterization and biological activity of Macfadyena unguis-cati (Bignoniaceae)[Pubmed: 10757425]

Macfadyena unguis-cati (L.) has been widely used in folk medicine as an anti-inflammatory, antimalarial and antivenereal. The purpose of this study was to chemically characterize the main plant components, and to evaluate the biological properties of some of the fractions derived from leaves (MACb) and liana (MACa) of this plant. Chemical characterization allowed the identification of the compounds Corymboside, vicenin-2, quercitrin, chlorogenic acid, isochlorogenic acid, lupeol, beta-sitosterol, beta-sitosterylglucoside, allantoin and lapachol. The biological screening of fractions and/or purified substances derived from fractions revealed antitumoral and antitrypanosomal activities in fractions MACa/lapachol and MACb/MACb21, respectively. The anti-lipoxygenase and anti-cyclooxygenase effect seen in fractions MACa and MACb showed a partial correlation with the anti-inflammatory property attributed to this plant.

Phytochemistry Volume 18, Issue 11, 1979, Pages 1899-1900

Corymboside, nouvelle di-C-glycosylflavone des racines de Carlina corymbosa[Reference: WebLink]

Corymboside, a new di-C-glycosylflavone from Carlina corymbosa roots, was shown to be 6-C-α-l-arabinopyranosyl-8-C-β-d-galactopyranosylapigenin by MS, CD, 1H and 13C NMR.