Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Food Chem.2021, 360:130063.
Front Pharmacol.2019, 10:1355
Phytomedicine.2020, 79, 153351
Antioxidants (Basel).2020, 9(6):526.
Front Pharmacol.2020, 11:683.
Biol Pharm Bull.2020, 43(10):1534-1541.
Pharmaceuticals (Basel).2020, 13(10):302.
Natural Product Communications2021, 16(9):1-10.
Chemistry of Vegetable Raw Materials2019, 3:119-127
J Pharmacol Sci.2021, 147(2):184-191.
International Journal of Mass Spectrometry, 2012, 315(1):46-54.
Collision induced dissociation study of the major components of silymarin.[Reference: WebLink
The fragmentation properties of the major silymarin constituents, including silydianin, silychristin A and Silychristin B
, silybin A and B and isosilybin A and B were studied by energy-dependent collision-induced dissociation (CID) technique.
METHODS AND RESULTS:
The survival yield (SY) method was applied to compare the fragmentation behavior of the various silymarin components. MS/MS spectra were recorded at collision energies which correspond to about 50% survival yield (CE50) and about 1% survival yield (CE01). The laboratory frame collision energy dependence of the fragmentation was studied on the basis of the breakdown curves, i.e., the relative intensities of fragment ions versus collision energy.
The fragmentation of silybins and isosilybins is distinct in spite of the minimal difference between their structures. This phenomenon, which is the basis of their analytical identification, is explained in details for the first time, on the basis of the energy-dependent MS/MS experiments and the conformational analysis.