7-beta-Hydroxylathyrol | CAS:34208-98-5

Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Asian J Beauty Cosmetol2020, 18(3): 265-272.

Arch Biochem Biophys.2020, 687:108384.

Molecules.2019, 25(1):E103

Planta Med.2019, 85(4):347-355

Dermatologica Sinica2024, 42(1):p19-30.

J Biochem Mol Toxicol.2022, e23211.

Molecules.2023, 28(13):4907.

Free Radic Biol Med.2016, 97:307-319

Appl. Sci.2020, 10,1304

Biomedicines.2024, 12(12):2928.

Journal of Molecular Catalysis B: Enzymatic, 2017:S1381117717300279.

Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis.[Reference: WebLink]

METHODS AND RESULTS:
The regioselective oxidation of three lathyrane diterpenoids (lathyrol, 1; 7-beta-Hydroxylathyrol, 2; and Euphorbia factor L3, 3) catalyzed by the fungi Mortierella ramanniana CGMCC 3.03413, Mucor circinelloides CICC 40242, and the actinomycete Nocardia iowensis sp. nov. NRRL 5646 was investigated. Ten new metabolites (4–13) including two unprecedented cyclopropane-rearranged products (4 and 5) have been obtained. Metabolites (6, 10 and 11) were further converted chemically to eight acylated derivatives (6a, 10a–10f and 11a).
CONCLUSIONS:
The structures of all compounds were elucidated on the basis of extensive NMR and MS data analyses. All the metabolites and enzyme-chemical products were evaluated for their cytotoxicities against three human cancer cell lines as well as their multidrug resistance (MDR) reversing effects in adriamycin (ADM)-resistant human MCF-7 breast cancer cells (MCF-7/ADM).

Product Name	7-beta-Hydroxylathyrol
CAS No.:	34208-98-5
Catalog No.:	CFN92488
Molecular Formula:	C₂₀H₃₀O₅
Molecular Weight:	350.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The seeds of Euphorbia lathyris L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$148/20mg