Euphorbia factor L7b
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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The 19th National Symposium on Organic Analysis and Bioanalysis of the Chinese Chemical Society.
Analysis of Lathyrane Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance[Reference:
WebLink]
METHODS AND RESULTS:
A series of lathyranediterpeneswere isolated or synthesized,and established on the basis of extensive spectroscopic methods,including two-dimensional NMR techniques.Stereo configuration and conformation of Euphorbia factors L1, Euphorbia factor L2, Euphorbia factor L7a, Euphorbia factor L7b , Euphorbia factor L8 and derivatives of L3 were analyzed by X-ray diffraction for the first time.The configuration of the unique isolathyrolditerpene Euphorbia factor L7b was rectified from S* to R* at C-5.
CONCLUSIONS:
All compounds were examined as modulators of multidrug resistance on MCF-7/ADM cell lines in vitro.To obtain sufficient information on the structural characteristics of this class of compounds,the detailed fragmentation patterns of the lathyranediterpenes were studied with collision-induced dissociation(CID)–MS/MS using an ESI–quadrupole time-of-flight(QTOF)–MS/MS hybrid instrument in positive-ion mode.
