Jolkinol A
Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
VNU J Sci: Med. Pharm. Sci.2024, 40(2):21-30.
Antioxidants (Basel).2021, 10(3):379.
Pak J Pharm Sci.2019, 32(6):2879-2885
Evid Based Complement Alternat Med.2016, 2016:1230294
Food and Agriculture Org. Of the UN2019, 151-160
Molecules.2022, 27(7):2093.
Evid Based Complement Alternat Med.2021, 2021:8707280.
Mol Med Rep.2014, 9(5):1653-9
J Nat Prod.2022, 85(5):1351-1362.
BMC Complement Altern Med.2017, 17(1):393
Related and Featured Products
Planta Med. 2004 Mar;70(3):244-9.
Euphopubescenol and euphopubescene, two new jatrophane polyesters, and lathyrane-type diterpenes from Euphorbia pubescens.[Pubmed:
15114502]
METHODS AND RESULTS:
Two known lathyrane derivatives, Jolkinol A ( 3) and Jolkinol A ( 4), whose (13)C-NMR spectra were assigned, were also isolated. Compounds 1 - 3 have been evaluated for their ability to inhibit the in vitro growth of three human tumour cell lines representing different tumour types, MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) and SF-268 (CNS cancer).
CONCLUSIONS:
They inhibited both MCF-7 and NCI-H460 cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM, but were found to be ineffective as growth inhibitors of the SF-268 cell line
5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone
Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
Trachelogenin 4'-O-beta-gentiobioside
Catalog No: CFN95235
CAS No: 106647-13-6
Price: $218/10mg
Vaccarin E
Catalog No: CFN95252
CAS No: 2252345-81-4
Price: $318/10mg
Grosvenorin 2''-glucoside
Catalog No: CFN95282
CAS No: N/A
Price: $318/5mg
3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal
Catalog No: CFN95293
CAS No: 60026-28-0
Price: $413/5mg
Dihydrophaseic acid 4'-O-beta-D-glucopyranoside
Catalog No: CFN95393
CAS No: 78914-56-4
Price: $318/5mg
1,3,4,6-Tetragalloylglucose
Catalog No: CFN95425
CAS No: 26922-99-6
Price: $318/10mg
Malabaricone A
Catalog No: CFN95477
CAS No: 63335-23-9
Price: $318/10mg
Oxytroflavoside D
Catalog No: CFN95491
CAS No: 1391144-83-4
Price: $318/10mg
Ganoderenic acid G
Catalog No: CFN95517
CAS No: 120481-73-4
Price: $318/5mg